DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11600 and MPL1

DIOPT Version :9

Sequence 1:	NP_650217.2	Gene:	CG11600 / 41555	FlyBaseID:	FBgn0038068	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_568295.2	Gene:	MPL1 / 831268	AraportID:	AT5G14180	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	415	Identity:	125/415 - (30%)
Similarity:	191/415 - (46%)	Gaps:	48/415 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLMELVIFFDWLLIVSGMPKVKFGLQNFTGRGKDYRI-------KVITGILI--IDKYGYSVETH 57
            |.:.::|||            ...|:....||...|:       ....||..  :..:||..|.|
plant    14 LALSVLIFF------------ALSLKTLEARGTFGRLAGQPPQRTAAGGICASSVHIFGYKCEEH 66

  Fly    58 TVRTGDGYILDMFRIP---SSPNCKEDGFKPSVLIQHGLISLADSFLVTGPRSGLPFMLADRCYD 119
            .|.|.|||||:|.|||   :.....:.|.:..||||||::....|:|:......||.:|||:.:|
plant    67 DVVTQDGYILNMQRIPEGRAGAVAGDGGKRQPVLIQHGILVDGMSWLLNPADQNLPLILADQGFD 131

  Fly   120 VWLSNSRGVRYSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALHFVCHSQGCTT 184
            ||:.|:||.|:|:||..|..||.|||.::|.|:...|||||.|:|...|.:: :|::.||.|  |
plant   132 VWMGNTRGTRFSRRHKYLNPSQRAFWNWTWDELVSYDLPAMFDHIHGLTGQK-IHYLGHSLG--T 193

  Fly   185 LLVLLSMKPE-YNRMIKTANMMAPAVFMKHARNKLMKMFGNIIMSMKDSSF----FGPLDAIRFL 244
            |:...|...: ....:::|.|::|..::.|....:..:.....::...|..    |.|...   |
plant   194 LIGFASFSEKGLVDQVRSAAMLSPVAYLSHMTTVIGDIAAKTFLAEATSILGWPEFNPKSG---L 255

  Fly   245 LSVFCK--CSKFKKLCAFMFILASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFR 307
            :..|.|  |.|....| :..:.........:|.:.|.|.||..|.:.||:...|..|..:..:.|
plant   256 VGDFIKAICLKAGIDC-YDLVSVITGKNCCLNASTIDLFLANEPQSTSTKNMIHLAQTVRDKELR 319

  Fly   308 PYDFGVM-RNKKLYNQDTPPDYPLENVRPQSPIHIYHSHGDDLVARKDIHILISKLDKAVLHD-- 369
            .|::|.. ||.|.|.|..||.|.:..:..:.|:...:...|.|...||:..|   ||:...||
plant   320 KYNYGSSDRNIKHYGQAIPPAYNISAIPHELPLFFSYGGLDSLADVKDVEFL---LDQFKYHDID 381

  Fly   370 ---VVFEK-WSHSDFLFAKLIKKVV 390
               |.|.| ::|:||:.....|.||
plant   382 KMNVQFVKDYAHADFIMGVTAKDVV 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11600	NP_650217.2	PLN02872	46..396	CDD:215470	115/364 (32%)
CG11600	NP_650217.2	Abhydro_lipase	46..104	CDD:282003	24/62 (39%)
MPL1	NP_568295.2	PLN02872	16..415	CDD:215470	124/413 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.020