DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11600 and Gm8978

DIOPT Version :9

Sequence 1:	NP_650217.2	Gene:	CG11600 / 41555	FlyBaseID:	FBgn0038068	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_001310180.1	Gene:	Gm8978 / 668106	MGIID:	3647649	Length:	399	Species:	Mus musculus

Alignment Length:	366	Identity:	111/366 - (30%)
Similarity:	174/366 - (47%)	Gaps:	16/366 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IIDKYGYSVETHTVRTGDGYILDMFRIP-SSPNCKEDGFKPSVLIQHGLISLADSFLVTGPRSGL 109
            ||..:.|..|.:.|.|.|||||.:.||| ...|......|..|...|||.|.|..::...|.:.|
Mouse    36 IIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSTAPKMVVFCLHGLFSTAGIWVSNPPDNSL 100

  Fly   110 PFMLADRCYDVWLSNSRGVRYSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALH 174
            .|:|||..|||||.|:||...:::|:.|......||.||:.||...||||:|.:||..|.::.::
Mouse   101 AFILADAGYDVWLGNNRGSTRAKKHVTLNTDSKEFWAFSYDEMIKYDLPAIIKFILEKTGQKQIY 165

  Fly   175 FVCHSQGCTTLLVLLSMKPEYNRMIKTANMMAPAVFMKHAR--NKLMKMFG----NIIMSMKDSS 233
            :..||||....|...:...|....||.:.::||...:|:.:  .:|...|.    .|:...|:
Mouse   166 YTGHSQGTLIALGAFATNQELAEKIKLSILIAPVHTVKYVKGAGRLPAYFTPTAFKIVFGEKE-- 228

  Fly   234 FFGPLDAIRFLLSVFCKCSKFKKLCAFMF-ILASEEPTSYMNNTAIPLILATHPGAISTRQPKHF 297
             |.|......|....|........||.:. .|....|..: |.:.|.:.:....|..|.:...|:
Mouse   229 -FFPTKVFSRLSQHVCDIKLVDAGCATVLGSLTGYSPEQF-NTSRIDVYITHSLGESSIQILIHY 291

  Fly   298 LQLRKSGKFRPYDFG-VMRNKKLYNQDTPPDYPLENVRPQSPIHIYHSHGDDLVARKDIHILISK 361
            .|..:||.|:.||:| ...|.:.|||.|||.|.:|:::  .|..::....|.|...:|:..|:.|
Mouse   292 GQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMK--VPTAMFSGLKDFLSNPEDVANLVPK 354

  Fly   362 LDKAVLHDVVFEKWSHSDFLFAKLIKKVVNEPIIKVIDHFE 402
            :.....|.::.: :||.||:.....:|.|:|.|:.::..::
Mouse   355 ISNLTYHKIISD-FSHLDFIMGLNARKEVSEEILTILRKYD 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11600	NP_650217.2	PLN02872	46..396	CDD:215470	111/358 (31%)
CG11600	NP_650217.2	Abhydro_lipase	46..104	CDD:282003	22/58 (38%)
Gm8978	NP_001310180.1	PLN02872	17..391	CDD:215470	111/361 (31%)
		Abhydro_lipase	33..94	CDD:282003	22/57 (39%)
		Abhydrolase_5	77..242	CDD:289465	54/167 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831789
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.960