DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11600 and Lip2

DIOPT Version :9

Sequence 1:	NP_650217.2	Gene:	CG11600 / 41555	FlyBaseID:	FBgn0038068	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_524667.1	Gene:	Lip2 / 43980	FlyBaseID:	FBgn0024740	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	121/390 - (31%)
Similarity:	181/390 - (46%)	Gaps:	62/390 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 IDKYGYSVETHTVRTGDGYILDMFRIPSSPNCKEDGFKPSVLIQHGLISLADSFLVTGPRSGLPF 111
            ::....|.|.|.|.|.|||.|.:.|:|..      |.|| ||:.|||:..:..::..||...|.|
  Fly    40 LEAQNVSHEVHNVTTADGYQLQLQRLPRL------GAKP-VLLVHGLLGSSLGWVCMGPERSLAF 97

  Fly   112 MLADRCYDVWLSNSRGVR-YSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTT------- 168
            .|..|.|||||:|.|||. |.::||.|......|||||:||.|..||||:||::...|
  Fly    98 QLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLAS 162

  Fly   169 ------NEEALH----FVCHSQGCTTLLVLLSMKPEYNRMIKTANMMAPAV-------FMKHARN 216
                  :||.:|    .:.|||.....|||.::.|.:|:.|:....:||..       |......
  Fly   163 RGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFDSFQVR 227

  Fly   217 KLMKMFGNIIMSMKDSSF--FGPLDAIRFLLSVFCK-CSKFKKLCAFMFILASEEPTSYMNNTAI 278
            :|||.   |....|...|  |.|        ..|.| |...:.||.:   .|.:...|..||.
  Fly   228 RLMKF---IKKRQKAYKFEIFPP--------GYFRKVCQAKRDLCEY---YAKQLVGSAQNNK-- 276

  Fly   279 PLILATHPGAI----STRQPKHFLQLRKSGKFRPYDFGVMRNKKLYNQDTPPDYPLENVRPQSPI 339
            .|:.|.:...:    |.|:.||..|:.|||.|..||||...|.::|:......|.:..:  ..||
  Fly   277 KLLEAFNYEYLLQGGSPREIKHLQQIWKSGDFISYDFGTAENLQVYHSVEALSYNISQI--TVPI 339

  Fly   340 HIYHSHGDDLVARKDIHILISKLDKAV--LHDVVFEKWSHSDFLFAKLIKKVVNEPIIKVIDHFE 402
            .:|....|.:...:.:|.:.:::.::|  :..:..:|::|.|||.:..:|.:||:   |:|:|.|
  Fly   340 ILYFGETDAIATPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVND---KLIEHME 401

Fly 403 402
Fly 402 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11600	NP_650217.2	PLN02872	46..396	CDD:215470	117/382 (31%)
CG11600	NP_650217.2	Abhydro_lipase	46..104	CDD:282003	19/56 (34%)
Lip2	NP_524667.1	PLN02872	24..407	CDD:215470	121/390 (31%)
Lip2	NP_524667.1	Abhydro_lipase	48..90	CDD:282003	18/48 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439558
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		otm46497
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	9	8.850