DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11600 and Lipk

DIOPT Version :9

Sequence 1:	NP_650217.2	Gene:	CG11600 / 41555	FlyBaseID:	FBgn0038068	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	XP_017444545.1	Gene:	Lipk / 294094	RGDID:	1309724	Length:	402	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	126/407 - (30%)
Similarity:	200/407 - (49%)	Gaps:	31/407 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 WLLIVSGM--PKVKFG--LQNFTGRGKDYRIKVITGILIIDKYGYSVETHTVRTGDGYILDMFRI 72
            |||....|  |...:|  .::.|....:..|..|....||..:||..|.|.|.|.|||||..:||
  Rat     3 WLLATCCMFLPGPIYGHMQESITNPEANMNIVCIFQSEIISYWGYPYERHDVVTEDGYILGTYRI 67

  Fly    73 PSSPNCKEDGF-KPSVLIQHGLISLADSFLVTGPRSGLPFMLADRCYDVWLSNSRGVRYSQRHIR 136
            |....|..... |..|.:|||||:.|.:::...|.:.|.|:|||..|||||.||||..:|::|:|
  Rat    68 PHGKGCSRKAVPKAVVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLR 132

  Fly   137 LKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALHFVCHSQGCTTLLVLLSMKPEYNRMIKT 201
            |......:|.||..||...||||.|:.||..:.::.|.:|.||||.|...:..|..||..:.|:.
  Rat   133 LSPKSPEYWAFSLDEMAKYDLPATINLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRM 197

  Fly   202 ANMMAPAVFMKHARNKLMK-----------MFGNIIMSMKDSSFFGPLDAIRFLLSVFCKCSKFK 255
            ...:||.|.:|:.::.:.|           :||       |..|.......:|:.:..|....|:
  Rat   198 FFALAPVVTVKYTQSPMKKLTTLSRKAVKILFG-------DKMFSTHTWLEQFIATKVCNRKLFR 255

  Fly   256 KLCA-FMFILASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFRPYDFG-VMRNKK 318
            :||: |:|.|:..:|.: :|.:.:.:.:|..|...|.:...|:.|...||:.:.:|:| ..:|..
  Rat   256 QLCSNFLFSLSGFDPQN-LNMSRLDVYMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMM 319

  Fly   319 LYNQDTPPDYPLENVRPQSPIHIYHSHGDDLVA-RKDIHILISKLDKAVLHDVVFEKWSHSDFLF 382
            .:||.|||.|.:..:|..:.:   .|.|.|:|| .||...|:.|:...:.:..: ..::|.||..
  Rat   320 HFNQLTPPVYNISKMRVPTAM---WSGGRDVVADEKDTKNLLPKVANLIYYKEI-PHYNHMDFYL 380

  Fly   383 AKLIKKVVNEPIIKVID 399
            .:...:.|...:|.:::
  Rat   381 GQDAPQEVYRDLITMME 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11600	NP_650217.2	PLN02872	46..396	CDD:215470	116/364 (32%)
CG11600	NP_650217.2	Abhydro_lipase	46..104	CDD:282003	25/58 (43%)
Lipk	XP_017444545.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335491
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.860