DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11600 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_650217.2	Gene:	CG11600 / 41555	FlyBaseID:	FBgn0038068	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	396	Identity:	104/396 - (26%)
Similarity:	169/396 - (42%)	Gaps:	87/396 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IIDKYGYSVETHTVRTGDGYILDMFRI--PSSPNCKEDGFKPSVLIQHGLISLADSFL-VTGPRS 107
            |.:.:||.||.|.|||.|.:||.:.||  |.....|.:    .|...|||::.::.:: |.....
pombe    78 ICEAFGYRVEEHLVRTQDNFILCLHRITHPKQSQHKRE----VVYCHHGLMTNSELWVAVNESER 138

  Fly   108 GLPFMLADRCYDVWLSNSRGVRYSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEA 172
            .|||:|.:..|||||.|:||.:||::||..|...:.||.||..:|.|.|:|..:||||..|..|.
pombe   139 SLPFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYILRETGREK 203

  Fly   173 LHFVCHSQGCTTLLVLLSMKPEYNRMIKTANMMAPAVFMKHARN-----------KLM-KMFGN- 224
            |:::..|||....:..||:.|:.|..:.....:|||...|...|           |:| .:||.
pombe   204 LNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFSNYFVDYIVKVNPKIMYHLFGRR 268

  Fly   225 ----------------IIMSMKDSSFFGPLDAIRFLLS-VFCKCSKFKKLCAFMFILASEEPTSY 272
                            |.:.:.|.|       ::.|.: .....|..:|||.:..:.:..
pombe   269 CLLPSVTFWQNICYPPIFVKIVDVS-------LKILFNWDLSNISLNQKLCGYAHLYSFS----- 321

  Fly   273 MNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFRPYD--------FGVMRNKKLYNQDTPPDYP 329
                             |.:...|:||:.|:..|:.||        :| .|:.::      |.:|
pombe   322 -----------------SVKSVVHWLQIIKNCTFQLYDDDMALLAGYG-SRHYQV------PLFP 362

  Fly   330 LENVRPQSPIHIYHSHGDDLVARKDIHILISKLDKAVLHDVVFEKWSHSDFLFAKLIKKVVNEPI 394
            ..|::  .|:.|.....|.|:..:.:...:....|    :|....:.|.|||:.:.:|:.|...:
pombe   363 TNNIK--CPMLILWGGKDTLINMEVMRTALPPHAK----EVSIAHYEHLDFLWGQDVKEEVFPVV 421

  Fly   395 IKVIDH 400
            |..:.|
pombe   422 IDALKH 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11600	NP_650217.2	PLN02872	46..396	CDD:215470	102/390 (26%)
CG11600	NP_650217.2	Abhydro_lipase	46..104	CDD:282003	21/60 (35%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	20/56 (36%)
		Abhydrolase_1	116..410	CDD:278959	84/335 (25%)
		Abhydrolase	<171..>242	CDD:304388	25/70 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870