DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11598 and SPBC16A3.12c

DIOPT Version :9

Sequence 1:	NP_001036710.1	Gene:	CG11598 / 41554	FlyBaseID:	FBgn0038067	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_596777.1	Gene:	SPBC16A3.12c / 2539875	PomBaseID:	SPBC16A3.12c	Length:	443	Species:	Schizosaccharomyces pombe

Alignment Length:	368	Identity:	105/368 - (28%)
Similarity:	179/368 - (48%)	Gaps:	31/368 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EIIASHNYPVEVHTVLTRDGYLLDAFRIPGSKFCQQSGPKPAVLF-QHGMSASSDVFL-LNGPQD 85
            ||..:..|.||.|.|.|:|.::|...||...|   ||..|..|:: .||:..:|:::: :|..:.
pombe    77 EICEAFGYRVEEHLVRTQDNFILCLHRITHPK---QSQHKREVVYCHHGLMTNSELWVAVNESER 138

  Fly    86 SLAFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEAFWRFSWHEIGTEDVAAFIDYILDTTKQRA 150
            ||.|:|.::.:||||.|:||.:|||:|::..|.||.||.||..::...|:...:||||..|.:..
pombe   139 SLPFVLIESGYDVWLGNNRGNKYSRKHITYKPKDEEFWNFSLDDMAMFDIPDTVDYILRETGREK 203

  Fly   151 LHFLGHSQGCTTLVVLLSMRPEYNKLVKTAVLLAPAVFMRHTSTLSQTVFRSFIMAMPDKEFMYH 215
            |:::|.|||....:..||:.|:.|..|...:.||||...:..|    ..|..:|:.:..| .|||
pombe   204 LNYIGFSQGTAQAMAALSINPDLNDKVNIFIGLAPAYAPKGFS----NYFVDYIVKVNPK-IMYH 263

  Fly   216 NGVLNKLL------SNVC--GLFVARVFCTTFFLISNGKISK-HLNTSVIPLIAATLPAGVSSRQ 271
            ......||      .|:|  .:|| ::...:..::.|..:|. .||..:...  |.|.:..|.:.
pombe   264 LFGRRCLLPSVTFWQNICYPPIFV-KIVDVSLKILFNWDLSNISLNQKLCGY--AHLYSFSSVKS 325

  Fly   272 PKHFIQLTDSGKFRPFDFGILRNLINYKS--LEPPDYTLSNVRPLTPVHIFYSDDDSSTAKEDIQ 334
            ..|::|:..:..|:.:| ..:..|..|.|  .:.|.:..:|::  .|:.|.:...|:....|.::
pombe   326 VVHWLQIIKNCTFQLYD-DDMALLAGYGSRHYQVPLFPTNNIK--CPMLILWGGKDTLINMEVMR 387

  Fly   335 NFAARVPEVVMHRISTPGWHHTDFVHSMTVADVINKPVIEIFR 377
              .|..|..  ..:|...:.|.||:....|.:.:...||:..:
pombe   388 --TALPPHA--KEVSIAHYEHLDFLWGQDVKEEVFPVVIDALK 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11598	NP_001036710.1	Abhydro_lipase	21..82	CDD:282003	20/60 (33%)
CG11598	NP_001036710.1	PLN02872	22..384	CDD:215470	105/368 (29%)
SPBC16A3.12c	NP_596777.1	Abhydro_lipase	75..131	CDD:282003	20/56 (36%)
		Abhydrolase_1	116..410	CDD:278959	86/308 (28%)
		Abhydrolase	<171..>242	CDD:304388	26/70 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870