DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11598 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_001036710.1	Gene:	CG11598 / 41554	FlyBaseID:	FBgn0038067	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	409	Identity:	109/409 - (26%)
Similarity:	177/409 - (43%)	Gaps:	66/409 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SYKAFVFFC--LYID-----LAKGLITSEIIASHNYPVEVHTVLTRDGYLLDAFRIPGSK--FCQ 57
            |.|.:.:|.  |.:|     |.....|.::.|.|.|.:|.|.|.|.|||||...|:...|  ..:
pombe    49 SKKVYSYFLPELLVDDNANKLTDARDTIDLCALHGYDLEEHFVRTTDGYLLGLHRVYKKKKGKIE 113

  Fly    58 QSGPKPAVLFQHGMSASSDVFLLN-GPQDSLAFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEA 121
            :....|.|||.||:..:|:.::.| ..:|::.|.|.:..:||||.|.||.:||.:::.....:..
pombe   114 ELNYLPPVLFIHGLMMNSESWVCNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPK 178

  Fly   122 FWRFSWHEIGTEDVAAFIDYILDTTKQRALHFLGHSQGCTTLVVLLSMRPEYNKLVKTAVLLAPA 186
            ||.||...|...|:.:.:.|||......::..:|.|||.......||:..|....|:..:.||||
pombe   179 FWDFSLDSIAIFDIPSIVKYILSVNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPA 243

  Fly   187 VFMRHTSTLSQTVFRSFIMAMPDKEFMY----HNGVLNK-----------LLSNVCGLFVARVFC 236
            :..:..|  .:|| :|.|.|  :.:.:|    .|.:|..           :.:.:..||:
pombe   244 IAPKKYS--GRTV-KSIIHA--NSQLLYLMFGRNSMLGSAVFWQAVLYPPVFAKIVDLFL----- 298

  Fly   237 TTFFLISNGKISKHLNTSVIPLIAA--TLPAGVSSRQPKHFIQLT---------DSGKFRPFDFG 290
             .|||...||     |.|....|.|  .|.:..|.:...|:.|:|         ||..|:|..:.
pombe   299 -RFFLSWTGK-----NISETQKIVAYSHLYSFTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYT 357

  Fly   291 ILRNLINYKSLEPPDYTLSNVRPLTPVHIFYSDDDSSTAKEDIQNFAARVPEVVMHRISTPGWHH 355
            .|..:..        |.:.|:|  .|:.:.|..:|:..   ||:....::|. :...|..|.:.|
pombe   358 NLNRIAR--------YPIENIR--LPITLVYGSNDNMV---DIETLKTQLPP-LSQCIQIPNYEH 408

  Fly   356 TDFVHSMTVADVINKPVIE 374
            .|.:...|..|::.:.|:|
pombe   409 LDIIMGDTKKDIVIQQVVE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11598	NP_001036710.1	Abhydro_lipase	21..82	CDD:282003	23/63 (37%)
CG11598	NP_001036710.1	PLN02872	22..384	CDD:215470	102/382 (27%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	22/62 (35%)
		Abhydrolase_1	119..412	CDD:278959	84/322 (26%)
		Abhydrolase_5	120..>260	CDD:289465	45/142 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870