DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11598 and Lipa

DIOPT Version :9

Sequence 1:	NP_001036710.1	Gene:	CG11598 / 41554	FlyBaseID:	FBgn0038067	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_036864.3	Gene:	Lipa / 25055	RGDID:	3008	Length:	397	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	122/379 - (32%)
Similarity:	190/379 - (50%)	Gaps:	19/379 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IDLAKGLITSEIIASHNYPVEVHTVLTRDGYLLDAFRIP-GSKFCQQSGPKPAVLFQHGMSASSD 76
            :|....:..:|||....||.|.|:|.|.|||:|...||| |.|.....||||.|..|||..|.|.
  Rat    27 VDPEANMNVTEIIMHWGYPGEEHSVQTGDGYILGVHRIPHGRKNQFDKGPKPVVYLQHGFLADSS 91

  Fly    77 VFLLNGPQDSLAFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEAFWRFSWHEIGTEDVAAFIDY 141
            .::.|...:||.|:||||.||||:.||||..:||:|.:|..|.:.:|.||:.|:...|:.|.|:|
  Rat    92 NWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINY 156

  Fly   142 ILDTTKQRALHFLGHSQGCTTLVVLLSMRPEYNKLVKTAVLLAPAVFMRHTSTLSQTVFRSFIMA 206
            ||:.|.|..|:::|||||||...:..|..||..|.||....|||.:.:...|.....:.|
  Rat   157 ILNKTGQEQLYYVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASGPMVKLGR----- 216

  Fly   207 MPD---------KEFMYHNGVLNKLLSNVCGLFVARVFCTTFFLISNGKISKHLNTSVIPLIAAT 262
            :||         |:|:..:.::..|.:::|...:.:..|...|.:..|...|:||.|.:.:....
  Rat   217 LPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTH 281

  Fly   263 LPAGVSSRQPKHFIQLTDSGKFRPFDFGIL-RNLINYKSLEPPDYTLSNVRPLTPVHIFYSDDDS 326
            .|||.|.:...|:.|:....|.:.||:|.. :|..:|....||.|::.:::  .|..::....|.
  Rat   282 CPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQ--LPTALWSGGKDW 344

  Fly   327 STAKEDIQNFAARVPEVVMHRISTPGWHHTDFVHSMTVADVINKPVIEIFRSFE 380
            .....||......:|.:|.|: :.|.|.|.||:..:.....:...|:.:.:.::
  Rat   345 LADTSDINILLTEIPTLVYHK-NIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11598	NP_001036710.1	Abhydro_lipase	21..82	CDD:282003	28/61 (46%)
CG11598	NP_001036710.1	PLN02872	22..384	CDD:215470	121/370 (33%)
Lipa	NP_036864.3	PLN02872	7..394	CDD:215470	122/374 (33%)
		Abhydro_lipase	35..96	CDD:282003	28/60 (47%)
		Abhydrolase_5	78..>203	CDD:289465	57/124 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335501
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860