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Protein Alignment Not10 and Cnot10

DIOPT Version :10

Sequence 1:	NP_650215.1	Gene:	Not10 / 41552	FlyBaseID:	FBgn0260444	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_705813.2	Gene:	Cnot10 / 78893	MGIID:	1926143	Length:	744	Species:	Mus musculus

Alignment Length:	703	Identity:	175/703 - (24%)
Similarity:	301/703 - (42%)	Gaps:	123/703 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 DENYSLLCQAHEQFNNSEFDRCLELLQELETRGESSGPVLRHNRAVVSYYKTGCTQHSVLLKELE 79
            |:...|...|.:.|.:..:|.||:.|..|:...:....::. |.||..::|...|....|.:.|.
Mouse    25 DQEKELSASALQAFTSGNYDACLQHLACLQDINKDDYKIIL-NTAVAEFFKNNQTTTDNLRQTLN 88

  Fly    80 ALTADADAPGDVSSGLSLKQGAAAATVARYNRAVIYYHRHMFGTALEKLAPLVARLEALEKAMAA 144
            .|.....:..:...||...:.    ::..||:|||.||...:..|:.....|...:|..|:..|.
Mouse    89 QLKNQVHSAVEEMDGLDDVEN----SMLYYNQAVILYHLRQYTEAISVGEKLYQFIEPFEEKFAQ 149

  Fly   145 LVATLQLQLLLATNQLNRAEAFLDYLQYKLNLVATAPSSNAAEEAAVVGTAPPSAATNSSVVASP 209
            .|..|.:.|.:.|:|..:|...|..|:..::  ..:...|...|     |...|:...|:..|.
Mouse   150 AVCFLLVDLYILTHQAEKALHLLAVLEKMIS--QGSGGKNGKNE-----TGNNSSKDGSNPKAE- 206

  Fly   210 GGAAVEGAVPGL-----GGSLQLLQLITLVLNRKPVVIQEDGTPEYAALKAQQYYIMKDFQMAAK 269
            ..|.:|.|...:     .|.:|:..|.......|.|:.....:.....||:...|:..:::.|.|
Mouse   207 SAALIEAAKSKIHQYKVRGYIQMKSLKACKREIKSVMNTAGNSAPSLFLKSNFEYLRGNYRKAVK 271

  Fly   270 QLMRINNECTQAGTI-TPQLSTCIA-NNMGVIHLRVRHYAIAAKFFQNALNFDQQLARNLRQS-- 330
             |:..:|.....|.: |.:...|:. ||:|.||..:..:.:...:|:.||..:..:...|...
Mouse   272 -LLNSSNIAEHPGFMKTGECLRCMFWNNLGCIHFAMSKHNLGIFYFKKALQENDNVCAQLSAGGT 335

  Fly   331 ---------TLQTMSSARSCEILYNLGVAMLHLRRPKEAFQCFLVPVKQFHSNPRLWLRMAEACI 386
                     .:.|:.:.:..|:|||.|:.:||:.||..||:|.:..|:.:|:|||||||:||.||
Mouse   336 DPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHVGRPLAAFECLIEAVQVYHANPRLWLRLAECCI 400

  Fly   387 MEHEAKLVEEER-----------------------QSQSETPSTKPYAPQSAGVPEPTLEFAVLC 428
            ..::....:|.:                       .||| ..:|.....||:.:|..::|||.:|
Mouse   401 AANKGTSEQETKGLPTKKGIVQSIVGQGYHRKIVLASQS-IQNTVYNDGQSSAIPVASVEFAAIC 464

  Fly   429 LRSALTLTQHYKTRFHMAAVSSEDVEAPEPKDPTQE-----------SWRHPQDNNFCN------ 476
            ||:||.|...                  |.:||.||           :....:.:..|:
Mouse   465 LRNALLLLPE------------------EQQDPKQENGSKSSSQLGGNTESSESSETCSSKSHDG 511

  Fly   477 -------PSKPVSLESLENMMAAIYAAHSFVSLRLGDHVTALEMSEKLLACERLSDAHKLLGHMY 534
                   ||.|:..:.|||:..:|.|..::|:|.|||::.||..:::||...:||.:.|.|||:|
Mouse   512 DKFIPAPPSSPLRKQELENLKCSILACSAYVALALGDNLMALNHADQLLQQPKLSGSLKFLGHLY 576

  Fly   535 AGEALMLMDKASEARDHLDPTFV------------------GTLNAFDFETR---DWQLKSVDAA 578
            |.|||:.:|:.|:|..||:|..|                  |...|.:...:   .....||::|
Mouse   577 AAEALISLDRISDAITHLNPENVTDVSLGISSNEQDQGSDKGENEAMESSGKRAPQCYPSSVNSA 641

  Fly   579 QNVVRYNLAVAMALQNDLPQAKALL---ANLTH-SLVANKALALRRFMDLKMG 627
            :.|:.:||..|..|:::..:|:..|   |::.| ..|..:|:.|..:::|:.|
Mouse   642 RTVMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEVPPEAILLAVYLELQNG 694

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.