DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha55 and VAB1

DIOPT Version :9

Sequence 1:	NP_001163597.1	Gene:	Vha55 / 41550	FlyBaseID:	FBgn0005671	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_177729.1	Gene:	VAB1 / 843934	AraportID:	AT1G76030	Length:	486	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	379/468 - (80%)
Similarity:	415/468 - (88%)	Gaps:	3/468 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKN 88
            :.|:|||||.|||||||:||.||:.|||.:||.||:.|.||||||.|.||||||||||||||.|.
plant    17 MEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKF 81

  Fly    89 TLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGI 153
            |..:|||::|:||||.|||||:|||||||||.|||||.|.:|||.|..|||..|.||||||||||
plant    82 TTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGI 146

  Fly   154 SAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKSV--LDDH-TDNFAIVFAAMG 215
            |.||||||||||||||:|||||||||||||||||||||||...|:|  |:|| .|||||||||||
plant   147 STIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTVDLLEDHGEDNFAIVFAAMG 211

  Fly   216 VNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDM 280
            ||||||:|||:|||||||||.|.||||||||||||||||||:|||.||:|||:|.||||||||||
plant   212 VNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDM 276

  Fly   281 SSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPI 345
            ||||:|||||||||||||||||:|||||||||||||||||:|||.|||||||||||||||||||.
plant   277 SSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPT 341

  Fly   346 PDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGK 410
            |||||||||||||:||||||||||||:||||||||||||||||||||||||||||||||.|||||
plant   342 PDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGK 406

  Fly   411 DVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKRI 475
            ||||||||||||||:.:||||||||.|||:.|:.||.|:.|.:|:|||:.|.||||||:|:|.||
plant   407 DVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHRI 471

  Fly   476 PASILAEFYPRDS 488
            ||..|.:||.|||
plant   472 PAKTLDQFYSRDS 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha55	NP_001163597.1	V-ATPase_V1_B	25..488	CDD:273410	377/465 (81%)
VAB1	NP_177729.1	V-ATPase_V1_B	18..486	CDD:273410	379/467 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	405	1.000	Domainoid score	I134
eggNOG	1	0.900	-	-		E1_COG1156
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1279
Inparanoid	1	1.050	753	1.000	Inparanoid score	I106
OMA	1	1.010	-	-		QHG62168
OrthoDB	1	1.010	-	-		D541116at2759
OrthoFinder	1	1.000	-	-		FOG0001501
OrthoInspector	1	1.000	-	-		otm2434
orthoMCL	1	0.900	-	-		OOG6_100544
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1067
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740