DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha55 and VAB3

DIOPT Version :9

Sequence 1:	NP_001163597.1	Gene:	Vha55 / 41550	FlyBaseID:	FBgn0005671	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_173451.5	Gene:	VAB3 / 838614	AraportID:	AT1G20260	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	377/469 - (80%)
Similarity:	414/469 - (88%)	Gaps:	4/469 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKN 88
            :.|:|||||.|||||||:||.||:.|||.:||.||:.|.||||||.|.||||||||||||||.|.
plant    17 MEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKF 81

  Fly    89 TLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGI 153
            |..:|||::|:||||.|||||:|||||||||.|||||.|.:|||.|..|||..|.||||||||||
plant    82 TTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGI 146

  Fly   154 SAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKS---VLDDH-TDNFAIVFAAM 214
            |.||||||||||||||:|||||||||||||||||||||||...|:   :.:|| .||||||||||
plant   147 STIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTENLIQEDHGEDNFAIVFAAM 211

  Fly   215 GVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTD 279
            |||||||:|||:|||||||||.|.||||||||||||||||||:|||.||:|||:|.|||||||||
plant   212 GVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTD 276

  Fly   280 MSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHP 344
            |||||:|||||||||||||||||:|||||||||||||||||:|||.|||||||||||||||||||
plant   277 MSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHP 341

  Fly   345 IPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIG 409
            .|||||||||||||:||||||||||||:||||||||||||||||||||||||||||||||.||||
plant   342 TPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIG 406

  Fly   410 KDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKR 474
            |||||||||||||||:.:||||||||.|||:.|:.||.|:.|.:|:|||:.|.||||||:|:|.|
plant   407 KDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHR 471

  Fly   475 IPASILAEFYPRDS 488
            |||..|.:||.|||
plant   472 IPAKTLDQFYSRDS 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha55	NP_001163597.1	V-ATPase_V1_B	25..488	CDD:273410	375/466 (80%)
VAB3	NP_173451.5	V-ATPase_V1_B	18..487	CDD:273410	377/468 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	405	1.000	Domainoid score	I134
eggNOG	1	0.900	-	-		E1_COG1156
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1279
Inparanoid	1	1.050	753	1.000	Inparanoid score	I106
OMA	1	1.010	-	-		QHG62168
OrthoDB	1	1.010	-	-		D541116at2759
OrthoFinder	1	1.000	-	-		FOG0001501
OrthoInspector	1	1.000	-	-		otm2434
orthoMCL	1	0.900	-	-		OOG6_100544
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1067
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740