DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha55 and VAB2

DIOPT Version :9

Sequence 1:	NP_001163597.1	Gene:	Vha55 / 41550	FlyBaseID:	FBgn0005671	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001190954.1	Gene:	VAB2 / 830008	AraportID:	AT4G38510	Length:	494	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	375/468 - (80%)
Similarity:	414/468 - (88%)	Gaps:	3/468 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKN 88
            :.|:|||||.||||||::||.||:.|||.:||.|||.|.||||||.|.||||||||||||||.|.
plant    25 MEYRTVSGVAGPLVILEKVKGPKYQEIVNIRLGDGTTRRGQVLEVDGEKAVVQVFEGTSGIDNKY 89

  Fly    89 TLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGI 153
            |..:|||::|:||||.|||||:|||||||||.|||||.|.:|||.|..|||..|.||||||||||
plant    90 TTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGI 154

  Fly   154 SAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKS--VLD-DHTDNFAIVFAAMG 215
            |.||||||||||||||:|||||||||||||||||||||||...||  :|: ...|||||||||||
plant   155 STIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKSDNLLEHQEDDNFAIVFAAMG 219

  Fly   216 VNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDM 280
            ||||||:|||:|||||||||.|.||||||||||||||||||:|||.||:|||:|.||||||||||
plant   220 VNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDM 284

  Fly   281 SSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPI 345
            ||||:|||||||||||||||||:|||||||||||||||||:|||.|||||||||||||||||||.
plant   285 SSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPT 349

  Fly   346 PDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGK 410
            |||||||||||||:||||||||||||:||||||||||||||||||||:|||||||||||.|||||
plant   350 PDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHSDVSNQLYANYAIGK 414

  Fly   411 DVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKRI 475
            ||||||||||||||:.:||||||||.|||:.|::||.|:.|.:|:|||:.|.||||||:|:|.||
plant   415 DVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVAQGAYDTRNIFQSLDLAWTLLRIFPRELLHRI 479

  Fly   476 PASILAEFYPRDS 488
            ||..|.:||.||:
plant   480 PAKTLDQFYSRDT 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha55	NP_001163597.1	V-ATPase_V1_B	25..488	CDD:273410	374/465 (80%)
VAB2	NP_001190954.1	V-ATPase_V1_B	26..491	CDD:273410	373/464 (80%)
		ATP-synt_ab_N	30..96	CDD:280947	47/65 (72%)
		V_A-ATPase_B	98..385	CDD:238555	243/286 (85%)
		ATP-synt_ab_C	401..492	CDD:278722	64/90 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	405	1.000	Domainoid score	I134
eggNOG	1	0.900	-	-		E1_COG1156
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	753	1.000	Inparanoid score	I106
OMA	1	1.010	-	-		QHG62168
OrthoDB	1	1.010	-	-		D541116at2759
OrthoFinder	1	1.000	-	-		FOG0001501
OrthoInspector	1	1.000	-	-		otm2434
orthoMCL	1	0.900	-	-		OOG6_100544
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1067
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740