Protein Alignment Vha55 and vha-12

DIOPT Version :10

• Sequence 1: NP_476908.1
• Gene: Vha55 / 41550
• FlyBaseID: FBgn0005671
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_508711.1
• Gene: vha-12 / 180692
• WormBaseID: WBGene00006921
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 477
• Identity: 415/477 - (87%)
• Similarity: 449/477 - (94%)
• Gaps: 3/477 - (0%)

  Fly    10 HVLAVSRDFISQPRLTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAV 74
            |..|:.|::.:.|||.|:||.|||||||||::||||:|:|||::.|.||:.|||||||:|.:|||
 Worm    13 HKSAIIRNYNTNPRLIYQTVCGVNGPLVILNDVKFPQFSEIVKITLPDGSKRSGQVLEISKNKAV 77

  Fly    75 VQVFEGTSGIDAKNTLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINP 139
            |||||||||||||||:|||||||||||||||||||:|||||||||||||:||||||||.||||||
 Worm    78 VQVFEGTSGIDAKNTICEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPPVLAEDFLDINGQPINP 142

  Fly   140 WSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKSVLDDHT 204
            ||||||||||||||||||||||||||||||||||:|||||||||||.||.|||:||.:   ....
 Worm   143 WSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSASGLPHNEIAAQIVRQGGLVQLPDR---PHEQ 204

  Fly   205 DNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQC 269
            .|||||||||||||||||||||||||||||||||||||||||||||||||||:|||:||||||||
 Worm   205 TNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRIALTSAEFLAYQC 269

  Fly   270 EKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPIL 334
            :|||||:||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||
 Worm   270 KKHVLVVLTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRDGSITQIPIL 334

  Fly   335 TMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVS 399
            ||||||||||||||||||||||||||||||||.||||:||||||||||||||||||||:||||||
 Worm   335 TMPNDDITHPIPDLTGYITEGQIYVDRQLHNRLIYPPINVLPSLSRLMKSAIGEGMTREDHSDVS 399

  Fly   400 NQLYACYAIGKDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLL 464
            |||||||||||||||||||||||||:.|||||||||||||||||:||:||||:||||||||||||
 Worm   400 NQLYACYAIGKDVQAMKAVVGEEALSSDDLLYLEFLTKFEKNFITQGHYENRSVFESLDIGWQLL 464

  Fly   465 RIFPKEMLKRIPASILAEFYPR 486
            ||||:|||||||.|.|.::|||
 Worm   465 RIFPREMLKRIPESTLEKYYPR 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha55	NP_476908.1	V-ATPase_V1_B	25..488	CDD:273410	409/462 (89%)
vha-12	NP_508711.1	V-ATPase_V1_B	29..489	CDD:273410	409/461 (89%)