DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and taar11

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001076546.1	Gene:	taar11 / 794647	ZFINID:	ZDB-GENE-041014-52	Length:	327	Species:	Danio rerio

Alignment Length:	325	Identity:	90/325 - (27%)
Similarity:	147/325 - (45%)	Gaps:	46/325 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 VFKAFVMLLIIIAAIC---GNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQV 215
            ||:|.:.||.|||.|.   |||.||.::...::|...|||.::|:|::|:::....|..:....:
Zfish    32 VFRAPLYLLFIIAIILIVFGNLWVICTISFFQQLHTPTNYLILSMAVSDLLLGSFVMPPSMLRSL 96

  Fly   216 TGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWIS 280
            ...|.|..|.|...::.|.....||:|||..||:|||||:.:|..|...||.||...|:|.:|..
Zfish    97 ETCWYFGDFFCKFHSATDFTLCNASVLHLVFISIDRYYAVCQPFHYQSRMTTRVSVFMILISWSF 161

  Fly   281 PALLSFLPIFIGWYTTPQH-QQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFRE 344
            .|...|..||.......:. ::..:.....|..:..:...|..|.:.:::|..|::..|..:|..
Zfish   162 SAFFGFGIIFSELKIEKKRTEELHVACKGGCLALHGREIGVTYSLVFYFLPMFIIVSLYSRVFII 226

  Fly   345 ANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKA 409
            |               |.|...:..:..:||.:                          |.:.||
Zfish   227 A---------------LKHVRVINSAASSLSAT--------------------------KMDLKA 250

  Fly   410 ARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFRE 474
            .:||.||:|.|:.||.|:|:...:...... .:|.::..:|.|:.|.|:..|||:||:|...||:
Zfish   251 TKTLAIIIGVFMSCWTPYFMCNIIDPIVNH-TIPALLYEVLMWVAYLNAVFNPLVYAFFYSWFRD 314

Fly 475 474
Zfish 315 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	53/181 (29%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	76/295 (26%)
taar11	NP_001076546.1	7tmA_TAAR1	49..313	CDD:320438	79/305 (26%)
		TM helix 2	69..95	CDD:320438	7/25 (28%)
		TM helix 3	107..137	CDD:320438	14/29 (48%)
		TM helix 4	149..172	CDD:320438	8/22 (36%)
		TM helix 5	197..226	CDD:320438	6/28 (21%)
		TM helix 6	245..275	CDD:320438	13/29 (45%)
		TM helix 7	284..309	CDD:320438	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000