DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and Npffr2

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_076470.1	Gene:	Npffr2 / 78964	RGDID:	620168	Length:	417	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	108/411 - (26%)
Similarity:	171/411 - (41%)	Gaps:	109/411 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 GLNFNESGAGLSDH---HHHQQHNPDEDWLD--NIVW---------VFKAFVMLLIIIAAIC--G 170
            |..::.:.:|..||   .:..||    .|..  ||.:         |...|:....:|..:|  |
  Rat     2 GKRWDSNSSGSWDHIWSGNDTQH----PWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCMVG 62

  Fly   171 NLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVY 235
            |.:|...|:|.|.:..:||:|:.:||::|::|.|..|.......:...|.|...:|.:...:...
  Rat    63 NTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKISGLVQGI 127

  Fly   236 FSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQ 300
            ...||:..|..|:|||:..:|.|.| | .:|.:...:|::..|       .|.|.|   .||...
  Rat   128 SVAASVFTLVAIAVDRFRCVVYPFK-P-KLTVKTAFVMIVIIW-------GLAITI---MTPSAI 180

  Fly   301 QFVIQNPTQCSFVVNKYYAV-ISS----SISFW------------IPCTIMIFT-YLAIFREANR 347
            ...:|.        .|||.| :||    |..:|            |..|::..| |||
  Rat   181 MLHVQE--------EKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLA------- 230

  Fly   348 QEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLH-----EVEQEHTPTKDKHLIKMKREH 407
               .|.:    .::|:         |..|:...|| :.|     .:||.|...|.:.:|||
  Rat   231 ---PLSL----IVIMY---------ARIGASLFKT-SAHSTGKQRLEQWHVSKKKQKVIKM---- 274

  Fly   408 KAARTLGIIMGTFILCWLPFFLWYTLSMTCE-------ECQVPDI-VVSILFWIGYFNSTLNPLI 464
              ..|:.::   |||.|||  || ||.|..:       :.:|.:| |.....|:.:.||::||:|
  Rat   275 --LLTVALL---FILSWLP--LW-TLMMLSDYADLSPNKLRVINIYVYPFAHWLAFCNSSVNPII 331

  Fly   465 YAYFNRDFREAFRNTLLCLFC 485
            |.:||.:||..|::..  .||
  Rat   332 YGFFNENFRSGFQDAF--QFC 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	54/197 (27%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	86/325 (26%)
Npffr2	NP_076470.1	7tm_4	53..>176	CDD:304433	37/134 (28%)
		7tm_1	62..332	CDD:278431	86/325 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910