Protein Alignment Octbeta2R and Gpr21

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001383750.1
• Gene: Gpr21 / 689917
• RGDID: 1586383
• Length: 349
• Species: Rattus norvegicus
• Alignment Length: 341
• Identity: 81/341 - (23%)
• Similarity: 144/341 - (42%)
• Gaps: 52/341 - (15%)

  Fly   154 VFKAFVMLLIIIAAICGNLLVIISVMRVRKL--RVITNYFVVSLAMADIMVAIMAMTFNFSVQVT 216
            :.:..:::.:.:..|.||::||. |.....|  ...|:||:.::|.||::|.:..:..:.|:...
  Rat    29 LLEVLIVVFLTVLIISGNIIVIF-VFHCAPLLNHHSTSYFIQTMAYADLLVGVSCLVPSLSLLYY 92

  Fly   217 GRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISP 281
            .........|.::..:.....:.|:..|.|||:|||.||.|||.|...:|...:.:.:...|:..
  Rat    93 PLPMEEAMTCQVFGFIVSVLKSISMASLACISIDRYIAITKPLTYNTLVTPWRLRLCIFLIWLYS 157

  Fly   282 ALLSFLPIFIGWYTTPQHQQFVIQNPTQC--SFVVNKYYAVISSSISFWIPCTIMI-FTYLAIFR 343
            .|: |||.|..|.....|....    ..|  |:..|.|:.:. ..::.:.|..::: |||..|||
  Rat   158 TLV-FLPSFFHWGKPGYHGDVF----RWCAESWHTNSYFTLF-IVMTLYAPAALIVCFTYFNIFR 216

  Fly   344 EANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHK 408
            ...:..|::..|..      |.|.| :||    :|.::|          .|.|           :
  Rat   217 ICQQHTKEISERQA------RFSSQ-NGE----TGEAQT----------CPDK-----------R 249

  Fly   409 AARTLGIIMGTFILCWLPFFLWYTL--SMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRD 471
            .|..|..|...|.:.|||:.:::.|  |..|..    .:...:..|:...||..|.:||:..|..
  Rat   250 YAMVLFRITSVFYVLWLPYIIYFLLESSTGCSS----RLASFLTTWLAISNSFCNCIIYSLSNSV 310

  Fly   472 FREAFR--NTLLCLFC 485
            |::..:  :..:|..|
  Rat   311 FQQGLKGLSESVCTSC 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	79/327 (24%)
		TM helix 1	155..181	CDD:320194	6/25 (24%)
		TM helix 2	188..214	CDD:320194	8/25 (32%)
		TM helix 3	226..256	CDD:320194	10/29 (34%)
		TM helix 4	268..291	CDD:320194	5/22 (23%)
		TM helix 5	315..344	CDD:320194	8/29 (28%)
		TM helix 6	404..434	CDD:320194	8/31 (26%)
		TM helix 7	444..469	CDD:320194	6/24 (25%)
Gpr21	NP_001383750.1	7tm_classA_rhodopsin-like	31..308	CDD:410626	77/319 (24%)
		TM helix 1	31..56	CDD:410626	6/25 (24%)
		TM helix 2	64..90	CDD:410626	8/25 (32%)
		TM helix 3	102..132	CDD:410626	10/29 (34%)
		TM helix 4	145..164	CDD:410626	4/19 (21%)
		TM helix 5	188..213	CDD:410626	6/25 (24%)
		TM helix 6	245..275	CDD:410626	9/40 (23%)
		TM helix 7	283..308	CDD:410626	6/24 (25%)