Protein Alignment Octbeta2R and drd1b

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001129448.1
• Gene: drd1b / 568126
• ZFINID: ZDB-GENE-070524-2
• Length: 446
• Species: Danio rerio
• Alignment Length: 336
• Identity: 122/336 - (36%)
• Similarity: 181/336 - (53%)
• Gaps: 37/336 - (11%)

  Fly   162 LIIIAAICGNLLVIISVMRVRKLR-VITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFL 225
            |:|:..:.||.||..:|.:.|.|| .:||:||:|||::|::|||:.|.:..:.::.|.|.|..|
Zfish    30 LLILTTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAISDLLVAILVMPWKAATEIVGFWPFGAF- 93

  Fly   226 CDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIF 290
            ||:|.:.|:..||||||:||.||||||:||..|.:|...||.:|..||:...|....|:||:|:.
Zfish    94 CDVWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKVAFIMISVAWTLSILISFIPVQ 158

  Fly   291 IGWYTTPQHQQFVIQN-------PTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQ 348
            :.|:.. |...:...|       |..|...:|:.||:.||.|||:||..||:.||..|:|.|.:|
Zfish   159 LNWHKA-QTTSYTELNGTYGELPPDNCDSSLNRTYAISSSLISFYIPVAIMLVTYTRIYRIAQKQ 222

  Fly   349 EKQL-MMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAART 412
            .::: .:........:|.|...:..::....|.|                   :..|||.|..:|
Zfish   223 IRRISALERAAESAKNRHSSMGNNASMESESSFK-------------------MSFKRETKVLKT 268

  Fly   413 LGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIV------VSILFWIGYFNSTLNPLIYAYFNRD 471
            |.:|||.|:.||||||:...:...|...:..|.:      ..:..|.|:.||:|||:||| ||.|
Zfish   269 LSVIMGVFVCCWLPFFVLNCMVPFCNPNESTDFLCISSTTFDVFVWFGWANSSLNPIIYA-FNAD 332

  Fly   472 FREAFRNTLLC 482
            ||:||...|.|
Zfish   333 FRKAFSILLGC 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	118/328 (36%)
		TM helix 1	155..181	CDD:320194	7/18 (39%)
		TM helix 2	188..214	CDD:320194	12/25 (48%)
		TM helix 3	226..256	CDD:320194	19/29 (66%)
		TM helix 4	268..291	CDD:320194	8/22 (36%)
		TM helix 5	315..344	CDD:320194	15/28 (54%)
		TM helix 6	404..434	CDD:320194	16/29 (55%)
		TM helix 7	444..469	CDD:320194	11/30 (37%)
drd1b	NP_001129448.1	7tm_GPCRs	21..337	CDD:475119	118/328 (36%)
		TM helix 1	24..48	CDD:320443	7/17 (41%)
		TM helix 2	58..80	CDD:320443	11/21 (52%)
		TM helix 3	95..117	CDD:320443	12/21 (57%)
		TM helix 4	140..156	CDD:320443	6/15 (40%)
		TM helix 5	190..213	CDD:320443	12/22 (55%)
		TM helix 6	266..288	CDD:320443	12/21 (57%)
		TM helix 7	306..331	CDD:320443	11/25 (44%)