DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and LOC563567

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_005158584.1	Gene:	LOC563567 / 563567	-ID:	-	Length:	447	Species:	Danio rerio

Alignment Length:	362	Identity:	138/362 - (38%)
Similarity:	193/362 - (53%)	Gaps:	33/362 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 ESGAG-LSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLR-VITN 189
            |:|.. ..|..|..|...|.|. .|.|.....||:.|:|::.:.||.||..:|::.|.|| .:||
Zfish     8 ENGTNHTQDRAHGAQEREDGDG-QNSVRALLGFVLFLLIVSTLLGNTLVCAAVVKFRHLRSKVTN 71

  Fly   190 YFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYA 254
            :||:|||::|:.||::.|.:.....|.|.|.|..| |.:|.:.|:..||||||:||.||||||:|
Zfish    72 FFVISLAVSDLFVAVLVMPWEAISAVAGTWLFGRF-CGIWIAFDIMCSTASILNLCIISVDRYWA 135

  Fly   255 IVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQQFVIQNPT----QCSFVVN 315
            |..|.:|...||.||..:|:...|....|:||:|:.:.|:.....::....|.|    .|...:|
Zfish   136 IASPFRYERKMTHRVAFMMIGVAWTLSILISFIPVQLNWHMADDDEEGAGGNGTDYSDNCKANLN 200

  Fly   316 KYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSS 380
            :.||:.||.|||:||..|||.||..|||.|..|.:::...  ...:.|..:...|.:. |...|.
Zfish   201 RTYAISSSLISFYIPVIIMIATYTRIFRIAQTQIRRISSL--ERAVEHAQNHHQSNDC-SNENSL 262

  Fly   381 KTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDI 445
            ||                   ..|:|.|..:||.||||.|:.||||||:...:...| :| |.|.
Zfish   263 KT-------------------TFKKETKVLKTLSIIMGVFVFCWLPFFVLNCMVPFC-QC-VSDT 306

  Fly   446 VVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLC 482
            ..:|..|.|:.||:|||:||| ||.|||:||.:.|.|
Zfish   307 TFTIFVWFGWANSSLNPVIYA-FNADFRKAFSSILGC 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	75/182 (41%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	113/299 (38%)
LOC563567	XP_005158584.1	7tmA_D1-like_dopamine_R	35..336	CDD:320185	125/326 (38%)
		TM helix 1	36..62	CDD:320185	9/25 (36%)
		TM helix 2	70..97	CDD:320185	11/26 (42%)
		TM helix 3	107..137	CDD:320185	18/29 (62%)
		TM helix 4	149..169	CDD:320185	7/19 (37%)
		TM helix 5	200..230	CDD:320185	18/29 (62%)
		TM helix 6	267..297	CDD:320185	16/29 (55%)
		TM helix 7	305..330	CDD:320185	13/25 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010