Protein Alignment Octbeta2R and zgc:162592

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001076297.1
• Gene: zgc:162592 / 561993
• ZFINID: ZDB-GENE-030131-5400
• Length: 375
• Species: Danio rerio
• Alignment Length: 419
• Identity: 98/419 - (23%)
• Similarity: 158/419 - (37%)
• Gaps: 133/419 - (31%)

  Fly    93 SSTGGIALPLGTATPATHELNATQPFGGSGLNFNESGAGLSD-HHHHQQHNPDEDWLDNIVWVFK 156
            |.|..:::|                    .::||     ::| |...:.|.|           .|
Zfish     2 SDTTNVSIP--------------------AVDFN-----ITDLHRTLEAHRP-----------IK 30

  Fly   157 AFVMLLIIIAAICGNLLVIISVMRV-----RKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVT 216
            ..::.::.:....||:.|::.:...     |..|    ||::||..||...|::.|..|..|.:.
Zfish    31 IGIISVLGVMITLGNIAVVMVIASAVSGWSRNSR----YFLLSLTGADSAFALLIMPLNLCVSLI 91

  Fly   217 GRWNFSPF-LCDLWNSLDVYFSTASILHLC-----CISVDRYYAIVKPLKYPISMTKRVVGIMLL 275
            ..:|..|. .|.:     |.|..|:|...|     .||::||.|:..||||.:.:|:|...:::.
Zfish    92 KEYNAGPDPFCHI-----VAFFNATIYSTCMYTLATISLERYIAVFYPLKYSVLLTRRRALLLIS 151

  Fly   276 NTWISPALLSFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISF--------WIPCT 332
            .:|:.|.:|.| ||.........|.       ::.|.|.|..|   ||::|:        :.||:
Zfish   152 FSWVFPPVLLF-PISFPAGIIEVHF-------SRASLVCNPLY---SSNVSYSLTLTCFIFFPCS 205

  Fly   333 -IMIFTYLAIFREANRQEKQLMMRH--GNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTP 394
             ||.|..|.::..|.||..:| .||  |..   :||.:
Zfish   206 AIMTFCNLRLWVAAKRQRSKL-RRHSWGGG---YRPKV--------------------------- 239

  Fly   395 TKDKHLIKMKREHKAARTLGIIMGTFILCWLP---FFLWYTLSMTCEECQVPDIVVSILFWIGYF 456
                          |.|.|..:|..:..||.|   ..|:..:|.:.    ||:.:..|..|:...
Zfish   240 --------------ALRVLVPVMTVYYTCWTPCMVIMLYNAISGSA----VPEWIEFIAVWLPTS 286

  Fly   457 NSTLNPLIYAYFNRDFREAFRNTL--LCL 483
            |..||.:.|.:.|..||:.|...|  |||
Zfish   287 NGFLNCIFYFWINHSFRKKFHVVLQKLCL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	84/345 (24%)
		TM helix 1	155..181	CDD:320194	4/25 (16%)
		TM helix 2	188..214	CDD:320194	9/25 (36%)
		TM helix 3	226..256	CDD:320194	11/34 (32%)
		TM helix 4	268..291	CDD:320194	7/22 (32%)
		TM helix 5	315..344	CDD:320194	11/37 (30%)
		TM helix 6	404..434	CDD:320194	8/32 (25%)
		TM helix 7	444..469	CDD:320194	6/24 (25%)
zgc:162592	NP_001076297.1	7tm_classA_rhodopsin-like	30..299	CDD:410626	81/337 (24%)
		TM helix 1	30..55	CDD:410626	4/24 (17%)
		TM helix 2	63..90	CDD:410626	11/30 (37%)
		TM helix 3	102..132	CDD:410626	11/34 (32%)
		TM helix 4	145..164	CDD:410626	4/19 (21%)
		TM helix 5	189..214	CDD:410626	6/24 (25%)
		TM helix 6	240..265	CDD:410626	8/24 (33%)
		TM helix 7	274..299	CDD:410626	6/24 (25%)