Protein Alignment Octbeta2R and LOC561565

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_021332202.1
• Gene: LOC561565 / 561565
• -ID: -
• Length: 461
• Species: Danio rerio
• Alignment Length: 533
• Identity: 124/533 - (23%)
• Similarity: 214/533 - (40%)
• Gaps: 114/533 - (21%)

  Fly   111 ELNATQPFGGSGLNFN--ESGAGLSDHHHHQQHNPDEDWLDNIVWV----FKAFV-------MLL 162
            :||:|    ||...::  |:|..:|.:....:.|    :..||.:|    .:.||       .||
Zfish     7 DLNST----GSPPLYSPLENGQNISVNRSTFRPN----YYTNITYVDFYLHEPFVSAIFIVSYLL 63

  Fly   163 IIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCD 227
            |.|..:.||.:|...|:|.:.:|.:||.|:::||::|::|.|..|.......:...|.|...:|.
Zfish    64 IFIVCMMGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLVDNIITGWPFGSLVCK 128

  Fly   228 LWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIG 292
            |...:.....:||:..|..|:|||:..||.|.|..::::...:.|:::  |:. |:....|..:.
Zfish   129 LSGMVQGISVSASVFTLVAIAVDRFRCIVYPFKQKLTISTSTLIIIII--WVL-AISIMCPSGVM 190

  Fly   293 WYTTPQHQQFVI---QNPTQCSF---------VVNKYYAVISSSISFWIPCTIMIFTY----LAI 341
            ...|.:|:..::   .|.||..:         .:.|.|..:..:..:..|.|:::..|    :.:
Zfish   191 LQVTKEHRVSILLSDGNTTQPFYWCRENWPNQEMRKIYTTVLFANIYLAPLTLIVIMYARIGITL 255

  Fly   342 FREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKRE 406
            |:.:                |..|..| .|.:.|||||.|.....  .::....|.|.:|||
Zfish   256 FKTS----------------MPAPVSQ-VGTSGSGSGSGKQCRYE--SRQLVSRKKKRVIKM--- 298

  Fly   407 HKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILF-----WIGYFNSTLNPLIYA 466
                  |.::...|||.|||.:....||......:....|::|.|     |:.:.||::||:||.
Zfish   299 ------LLVVALLFILSWLPLWALMMLSDYASLSERQHRVINIYFYPLAHWLAFCNSSVNPIIYG 357

  Fly   467 YFNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRSSLRYDQRAKSVYSESYLNSTTPSHRRQSQ 531
            :||.:||:.|:.......|:....                             |..|.|||.|..
Zfish   358 FFNENFRKGFKAAFKLQLCSGHSG-----------------------------NRRTYSHRLQGN 393

  Fly   532 MV--DNLXYRDEALLTPIAQQQQRLAAGGSRLGGQLAAAAKDGRESKDAKDTGKDAGKGKSNVDC 594
            .|  .||         |:. :|..|..|..|.|..|..........|...:..:.:||.......
Zfish   394 AVLPANL---------PLT-KQTALETGAPRPGQGLIQGLVSVSNGKGLGERSQSSGKENMKEQD 448

  Fly   595 LAGDDVQEIQIEI 607
            |..:|::::..::
Zfish   449 LIMEDLEKVMYDL 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	45/193 (23%)
		7tm_1	170..465	CDD:278431	77/315 (24%)
LOC561565	XP_021332202.1	7tm_GPCRs	55..367	CDD:333717	87/342 (25%)
		TM helix 1	57..81	CDD:320095	8/23 (35%)
		TM helix 2	90..112	CDD:320095	8/21 (38%)
		TM helix 3	128..150	CDD:320095	5/21 (24%)
		TM helix 4	171..187	CDD:320095	3/18 (17%)
		TM helix 5	226..249	CDD:320095	4/22 (18%)
		TM helix 6	293..318	CDD:320095	11/33 (33%)
		TM helix 7	335..360	CDD:320095	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910