Protein Alignment Octbeta2R and chrm2b

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_021326218.1
• Gene: chrm2b / 555516
• ZFINID: ZDB-GENE-090410-3
• Length: 476
• Species: Danio rerio
• Alignment Length: 504
• Identity: 122/504 - (24%)
• Similarity: 186/504 - (36%)
• Gaps: 162/504 - (32%)

  Fly   104 TATPATHELNATQPFGGSGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIA-- 166
            |.:|::...|.|..|                     |..|           ||....:||::.
Zfish     7 TLSPSSSHANKTNIF---------------------QDGP-----------FKPVEFVLIVLGLS 39

  Fly   167 -----AICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLC 226
                 .|.||:||::|:...|.|:.:.|||:.|||.||:.:.:.:|.......|||.|.....:|
Zfish    40 ILSLITIIGNVLVMLSIKVNRNLQTVNNYFLFSLACADLFIGVFSMNLYTVYIVTGHWPLGALVC 104

  Fly   227 DLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWI------SPALLS 285
            |||.:||...|.||:::|..||.|||:.:.|||.||:..|.::.|:|:...||      :||:|
Zfish   105 DLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVKRTHKMAGMMIAAAWILSFILWAPAIL- 168

  Fly   286 FLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIF-------- 342
            |.....|..|.|:.:.::       .|..|......::..:|::|...|...|..|.
Zfish   169 FWQFITGSRTVPEGECYI-------QFFSNAVVTFGTAIAAFYLPVITMTILYWQISKASRSRVR 226

  Fly   343 REANRQEKQLMMRHGNAML-----MHRPSMQ-------------------------PSGE----- 372
            |..||:..::....|.|.|     |.|.|.|                         |:||
Zfish   227 RRDNRRVSRVSNDGGQAGLGNERNMDRKSTQEGEEMVSRKQSASDTTTGLKISLFPPAGEERDSE 291

  Fly   373 --ALSGS--------------------------------------------GSSKTL-TLHEVEQ 390
              ::|||                                            .|.|.| ..::|..
Zfish   292 NDSISGSVLASSNQRDDEAVSISTNGDIRARQNQSASLATESWVRFTCFKTASQKDLQNTYKVNS 356

  Fly   391 EH------------------TPTKDKHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTC 437
            |.                  :|...|......||.|..||:..|:..|...|.|:.:...::..|
Zfish   357 ESQGMTNGKERLSLVSQKIISPHSQKRKSSSSREKKVTRTIMAILVAFATTWTPYNVMVLINTFC 421

  Fly   438 EECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLCLFCN 486
            .:| :|:.|....:|:.|.|||:||..||..|..|:..|:..|.|.:.|
Zfish   422 SDC-IPNTVWIFGYWLCYINSTVNPACYALCNVTFKNTFKQLLTCKYRN 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	59/190 (31%)
		7tm_1	170..465	CDD:278431	102/408 (25%)
chrm2b	XP_021326218.1	7tmA_mAChR_M2	32..459	CDD:320424	109/435 (25%)
		TM helix 1	33..59	CDD:320424	8/25 (32%)
		TM helix 2	66..92	CDD:320424	9/25 (36%)
		TM helix 3	104..134	CDD:320424	15/29 (52%)
		TM helix 4	146..169	CDD:320424	7/23 (30%)
		TM helix 5	191..220	CDD:320424	6/28 (21%)
		TM helix 6	264..418	CDD:320424	22/153 (14%)
		TM helix 7	427..452	CDD:320424	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910