Protein Alignment Octbeta2R and Octbeta1R

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_651057.1
• Gene: Octbeta1R / 42652
• FlyBaseID: FBgn0038980
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 244/540 - (45%)
• Similarity: 312/540 - (57%)
• Gaps: 85/540 - (15%)

  Fly    59 LTTLARVTA-AALTTAAMLHTTNALAATGSSSASNSSTGGIALPLGTATPATHELNATQ----PF 118
            :|.|.|:.| :|.||..:|.        ||.|   |..||...||.:..|...| :|:.    .|
  Fly     1 MTLLQRLQAMSATTTRTILE--------GSIS---SFGGGTNEPLASKIPVLEE-SASHARYLKF 53

  Fly   119 GGSGLNFNES-----GAGLS--------------DHHHHQQHNPDEDWLDNIVWVF-KAFVMLLI 163
            ...|| .:|.     |:|.|              |....:....|.|...::..|| |.|::..|
  Fly    54 IADGL-IDEGLGSAVGSGSSIAVSVEDVVAGQAQDIQASEGSTDDADGSSHLALVFVKCFIIGFI 117

  Fly   164 IIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDL 228
            |:|||.||:|||:||||.||||:||||||||||:||::||:.|||||.||.::|:|.|...:||:
  Fly   118 ILAAILGNMLVIVSVMRHRKLRIITNYFVVSLAVADMLVALCAMTFNASVMISGKWMFGSVMCDM 182

  Fly   229 WNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGW 293
            |||.|||||||||:||||||||||||||:||.||:.||:|.|.||||..|:||||||||||..||
  Fly   183 WNSFDVYFSTASIMHLCCISVDRYYAIVQPLDYPLIMTQRRVFIMLLMVWLSPALLSFLPICSGW 247

  Fly   294 YTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGN 358
            |||.::.:::..||..|.|.|||.||::|||:|||||..:|:..|..|::||:|||:.:......
  Fly   248 YTTTENYKYLKSNPHICEFKVNKAYAIVSSSMSFWIPGIVMLSMYYRIYQEADRQERLVYRSKVA 312

  Fly   359 AMLMHR-------PSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGII 416
            |:|:.:       |..:||               .:|||....|       |:||.|||||||||
  Fly   313 ALLLEKHLQISQIPKPRPS---------------IQVEQSTIST-------MRRERKAARTLGII 355

  Fly   417 MGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLL 481
            |..|::|||||||||.:|..|:.|..|.::|.||||||||||.|||:||||||||||.||:.||.
  Fly   356 MSAFLICWLPFFLWYIVSSLCDSCITPRLLVGILFWIGYFNSALNPIIYAYFNRDFRAAFKKTLK 420

  Fly   482 CL------FCNWWKDRHLPLDIDIRRSSLRYDQRAKSVYSES-----YLNSTTPSHRRQSQMVDN 535
            .|      ||...:.|....|::....|.|....|:...|.|     .:|||..|....|.|
  Fly   421 SLFPYAFYFCRRGRGRDDDRDLEFGGPSRRGTNGAQRTGSGSAEMANCVNSTASSEIHMSVM--- 482

  Fly   536 LXYRDEAL-LTPI--AQQQQ 552
              .|..|: :||.  ||.||
  Fly   483 -RARQYAVNVTPTTDAQMQQ 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	186/328 (57%)
		TM helix 1	155..181	CDD:320194	16/26 (62%)
		TM helix 2	188..214	CDD:320194	19/25 (76%)
		TM helix 3	226..256	CDD:320194	26/29 (90%)
		TM helix 4	268..291	CDD:320194	17/22 (77%)
		TM helix 5	315..344	CDD:320194	15/28 (54%)
		TM helix 6	404..434	CDD:320194	22/29 (76%)
		TM helix 7	444..469	CDD:320194	18/24 (75%)
Octbeta1R	NP_651057.1	7tmA_DmOct-betaAR-like	109..415	CDD:320194	185/327 (57%)
		TM helix 1	109..135	CDD:320194	15/25 (60%)
		TM helix 2	142..168	CDD:320194	19/25 (76%)
		TM helix 3	180..210	CDD:320194	26/29 (90%)
		TM helix 4	222..245	CDD:320194	17/22 (77%)
		TM helix 5	269..298	CDD:320194	15/28 (54%)
		TM helix 6	343..373	CDD:320194	22/29 (76%)
		TM helix 7	383..408	CDD:320194	18/24 (75%)