Protein Alignment Octbeta2R and MC5R

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_005904.1
• Gene: MC5R / 4161
• HGNCID: 6933
• Length: 325
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 84/382 - (21%)
• Similarity: 153/382 - (40%)
• Gaps: 103/382 - (26%)

  Fly   123 LNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVI 187
            ||.|.:...||..:...:.:|.|| :...|.||     |.:.:.::..|:|||.::::.:.|...
Human    12 LNLNATEGNLSGPNVKNKSSPCED-MGIAVEVF-----LTLGVISLLENILVIGAIVKNKNLHSP 70

  Fly   188 TNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWN------FSPFLCDLWNSLDVYFSTASILHLCC 246
            ..:||.|||:||::|::.:.....::.:....:      |...:.::::|:......||:..|..
Human    71 MYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLA 135

  Fly   247 ISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQQFVIQNPTQCS 311
            |:||||..|...|:|...||.|..|.::...|      :|.                    |.|.
Human   136 IAVDRYVTIFYALRYHHIMTARRSGAIIAGIW------AFC--------------------TGCG 174

  Fly   312 FVVNKY----YAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGE 372
            .|...|    |.::.....|:....:::..|:.:|..|....|::....|.:....|.|||
Human   175 IVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQ---- 235

  Fly   373 ALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTC 437
                                                .|.|:.:::|.|.:||.||||..||.::|
Human   236 ------------------------------------GAVTVTMLLGVFTVCWAPFFLHLTLMLSC 264

  Fly   438 EE---CQVPDIVVSILFWIGYF---------NSTLNPLIYAYFNRDFREAFRNTLLC 482
            .:   |.         .::.:|         ||.::|||||:.:::.|:.|:..:.|
Human   265 PQNLYCS---------RFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICC 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	39/187 (21%)
		7tm_1	170..465	CDD:278431	66/316 (21%)
MC5R	NP_005904.1	7tm_4	43..>167	CDD:304433	32/128 (25%)
		7tm_1	53..295	CDD:278431	66/316 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910