Protein Alignment Octbeta2R and MC3R

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_063941.3
• Gene: MC3R / 4159
• HGNCID: 6931
• Length: 323
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 88/358 - (24%)
• Similarity: 140/358 - (39%)
• Gaps: 107/358 - (29%)

  Fly   156 KAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAI------MAMTFNFSVQ 214
            |..|.|.:.|.::..|:|||::|:|...|.....:|:.|||:||::|::      :.:....|..
Human    41 KPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDY 105

  Fly   215 VTGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWI 279
            :|....|...:.::::|:......|||.:|..|:||||..|...|:|...||.|....:::..|:
Human   106 LTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV 170

  Fly   280 SPALLSFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIF-------- 336
                                          |..|....:.|.|.| ...|.|.|.:|
Human   171 ------------------------------CCGVCGVVFIVYSES-KMVIVCLITMFFAMMLLMG 204

  Fly   337 -TYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHL 400
             .|:.:|..|....|::      |.|.....:.|                    |:|:..
Human   205 TLYVHMFLFARLHVKRI------AALPPADGVAP--------------------QQHSCM----- 238

  Fly   401 IKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEE---CQVPDIVVSILFWIGYF------ 456
                   |.|.|:.|::|.||.||.||||...|.:||..   |         :.:..:|
Human   239 -------KGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYC---------ICYTAHFNTYLVL 287

  Fly   457 ---NSTLNPLIYAYFNRDFREAFRNTLLCLFCN 486
               ||.::|||||:.:.:.|..||. :|| .||
Human   288 IMCNSVIDPLIYAFRSLELRNTFRE-ILC-GCN 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	45/192 (23%)
		7tm_1	170..465	CDD:278431	74/321 (23%)
MC3R	NP_063941.3	7tm_4	45..>170	CDD:304433	35/124 (28%)
		7tm_1	55..299	CDD:278431	74/321 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910