DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Octbeta2R and DopEcR

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	88/338 - (26%)
Similarity:	143/338 - (42%)	Gaps:	58/338 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 KAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWN 220
            ||.::.::.:|.:..|||:|.:....:....:.||:::|||:||::..::.:.|:....:||.|.
  Fly    18 KAVLISILGVAIVLSNLLIIATYANFKGPTEVINYYLLSLAIADLLCGLLVVPFSVYPALTGEWM 82

  Fly   221 FSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLS 285
            :...:|.....|:|.....|:.....||||||.|:.|||:|....||......::.||||.|||.
  Fly    83 YGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQCWMVFTWISAALLC 147

  Fly   286 FLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWI--PCTI-MIFTYLAIFREANR 347
            ..|| :| |:.|     :..|.|....:.....|..|::::..:  |..| ::..|..||
  Fly   148 CPPI-LG-YSMP-----IENNMTHICMLDWGNMAAYSATLAILVLGPSLISIVHNYGYIF----- 200

  Fly   348 QEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAART 412
                :|||...           |||.:.....:..|    .|....|:   |::..
  Fly   201 ----VMMRKIR-----------SGEPIHDKEYATAL----AENLSNPS---HMMSF--------- 234

  Fly   413 LGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILF-----WIGYFNSTLNPLIYAYFNRDF 472
              .::..|.:.|||:.|     :...|....|::.|.|.     |||..||....||....:..|
  Fly   235 --ALVFAFWVSWLPWIL-----LRLYEVVTGDVIQSTLINFAVVWIGILNSFWKILIMTSMSPQF 292

  Fly   473 REAFRNTLLCLFC 485
            |.|.|...|.:.|
  Fly   293 RIALRVFCLTICC 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	52/180 (29%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	78/302 (26%)
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	82/320 (26%)
		TM helix 1	18..42	CDD:410626	7/23 (30%)
		TM helix 2	51..73	CDD:410626	8/21 (38%)
		TM helix 3	89..111	CDD:410626	4/21 (19%)
		TM helix 4	134..150	CDD:410626	7/15 (47%)
		TM helix 5	174..197	CDD:410626	4/22 (18%)
		TM helix 6	230..252	CDD:410626	6/37 (16%)
		TM helix 7	264..289	CDD:410626	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010