Protein Alignment Octbeta2R and HTR4

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001035263.1
• Gene: HTR4 / 3360
• HGNCID: 5299
• Length: 428
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 139/367 - (37%)
• Similarity: 188/367 - (51%)
• Gaps: 68/367 - (18%)

  Fly   159 VMLL-----IIIAAICGNLLVIISVMRVRKLRVI-TNYFVVSLAMADIMVAIMAMTFNFSVQVTG 217
            |:||     :|:.||.|||||:::|...|:||.| ||||:||||.||::|:::.|.|.....|..
Human    20 VVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQD 84

  Fly   218 RWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAI-VKPLKYPISMTKRVVGIMLLNTWISP 281
            .|.:....|.:..||||..:||||.||||||:|||||| .:||.|...||...:.:||...|:.|
Human    85 IWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIP 149

  Fly   282 ALLSFLPIFIGWYTTP-----QHQQF-VIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLA 340
            ..:|||||..||....     :.::| ...|.|.|.|:|||.||:..|.::|:||..:|:..|..
Human   150 TFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYR 214

  Fly   341 IFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKR 405
            |:..|.....|:.|                   |..:|:|........:|..|     |  :|:.
Human   215 IYVTAKEHAHQIQM-------------------LQRAGASSESRPQSADQHST-----H--RMRT 253

  Fly   406 EHKAARTLGIIMGTFILCWLPFFLW--------YTLSMTCEECQVPDIVVSILFWIGYFNSTLNP 462
            |.|||:||.||||.|.|||.|||:.        ||         ||..|.:...|:||.||.|||
Human   254 ETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT---------VPGQVWTAFLWLGYINSGLNP 309

  Fly   463 LIYAYFNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRSSL 504
            .:||:.|:.||.||   |:.|.|:         |...||.|:
Human   310 FLYAFLNKSFRRAF---LIILCCD---------DERYRRPSI 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	81/185 (44%)
		7tm_1	170..465	CDD:278431	119/310 (38%)
HTR4	NP_001035263.1	7tm_1	36..312	CDD:278431	119/310 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D328277at33208
OrthoFinder	1	1.000	-	-		FOG0005484
OrthoInspector	1	1.000	-	-		otm40768
orthoMCL	1	0.900	-	-		OOG6_107218
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.820