DRSC/TRiP Functional Genomics Resources

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Protein Alignment Octbeta2R and Tbxa2r

DIOPT Version :9

Sequence 1:NP_001163596.2 Gene:Octbeta2R / 41549 FlyBaseID:FBgn0038063 Length:630 Species:Drosophila melanogaster
Sequence 2:NP_001264194.1 Gene:Tbxa2r / 21390 MGIID:98496 Length:341 Species:Mus musculus


Alignment Length:337 Identity:62/337 - (18%)
Similarity:114/337 - (33%) Gaps:120/337 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   165 IAAICGNLLVIISVMRVRKLRVITNYFVVS--LAMADIMVAIMAMTFNFSVQVTGRWNF---SPF 224
            :|.:||  ||:...:.:    ::|...|.|  .|:.|                   |..   |..
Mouse    63 LALLCG--LVLTDFLGL----LVTGAIVASQHAALLD-------------------WRATDPSCR 102

  Fly   225 LCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKR---VVGIMLLNTWISPALLSF 286
            ||.......|:|....:|....::.:|:..|.:|...|.:.::|   .||::    |::...|..
Mouse   103 LCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLV----WVAAGALGL 163

  Fly   287 LPIF-IGWYTT--PQHQQFVIQNPTQCSFVVNKYYAVISSS---ISFWIPCTIMIFTYLAIF--R 343
            ||:. :|.|:.  |....|:.....:...|....:|::.|:   :|..:. |:.:.|...::  |
Mouse   164 LPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLN-TVSVATLCRVYHTR 227

  Fly   344 EANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHK 408
            ||.::.:..                                  |||.                  
Mouse   228 EATQRPRDC----------------------------------EVEM------------------ 240

  Fly   409 AARTLGIIMGTFILCWLPF--FLWYTLSMTCEECQVPDIV-------------VSILFWIGYFNS 458
            ..:.:| ||....:||:|.  |:..||      .|.|.::             :.|...:..:|.
Mouse   241 MVQLVG-IMVVATVCWMPLLVFIMQTL------LQTPPVMSFSGQLLRATEHQLLIYLRVATWNQ 298

  Fly   459 TLNPLIYAYFNR 470
            .|:|.:|..|.|
Mouse   299 ILDPWVYILFRR 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Octbeta2RNP_001163596.2 7tm_4 164..>342 CDD:304433 38/190 (20%)
7tm_1 170..465 CDD:278431 57/325 (18%)
Tbxa2rNP_001264194.1 7tm_GPCRs 25..317 CDD:333717 62/337 (18%)
TM helix 1 27..51 CDD:320095
TM helix 2 63..85 CDD:320095 6/27 (22%)
TM helix 3 105..127 CDD:320095 3/21 (14%)
TM helix 4 149..165 CDD:320095 4/19 (21%)
TM helix 5 191..214 CDD:320095 4/23 (17%)
TM helix 6 238..263 CDD:320095 9/43 (21%)
TM helix 7 284..309 CDD:320095 5/24 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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