Protein Alignment Octbeta2R and Taar4

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001008499.1
• Gene: Taar4 / 209513
• MGIID: 2685072
• Length: 347
• Species: Mus musculus
• Alignment Length: 329
• Identity: 111/329 - (33%)
• Similarity: 168/329 - (51%)
• Gaps: 50/329 - (15%)

  Fly   160 MLLIIIAAI----CGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWN 220
            |.||:|.||    .||:.||||:...::|...||:.::|:|..|.:::.:.|.|:....:...|.
Mouse    36 MYLIMIGAIVMTMLGNMAVIISIAHFKQLHSPTNFLILSMATTDFLLSCVVMPFSMIRSIESCWY 100

  Fly   221 FSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLS 285
            |....|.:.:..|:...|.||.|||.|||||:||:..||.|...:|.||||:.||.:|..|...:
Mouse   101 FGDLFCKVHSCCDIMLCTTSIFHLCFISVDRHYAVCDPLHYVTQITTRVVGVFLLISWSVPIFFA 165

  Fly   286 FLPIF-----IGWYTTPQHQQFV--IQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFR 343
            |..:|     ||      .:.||  |.....|..:.||.:.|::|.|:|::|.|:|:..|:.||.
Mouse   166 FGLVFSELNLIG------AEDFVAAIDCTGLCVLIFNKLWGVLASFIAFFLPGTVMVGIYIHIFT 224

  Fly   344 EANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHK 408
            .|.:..:|:                       |:|......|.|.:.:.|         .|:|.|
Mouse   225 VAQKHARQI-----------------------GTGPRTKQALSESKMKAT---------SKKESK 257

  Fly   409 AARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFR 473
            |.:||.|:||.|:|||||||: .|::....:...|:.:.::..|:||||||.||:||..|...||
Mouse   258 ATKTLSIVMGVFVLCWLPFFV-LTITDPFIDFTTPEDLYNVFLWLGYFNSTFNPIIYGMFYPWFR 321

  Fly   474 EAFR 477
            :|.|
Mouse   322 KALR 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	109/326 (33%)
		TM helix 1	155..181	CDD:320194	12/24 (50%)
		TM helix 2	188..214	CDD:320194	7/25 (28%)
		TM helix 3	226..256	CDD:320194	15/29 (52%)
		TM helix 4	268..291	CDD:320194	10/27 (37%)
		TM helix 5	315..344	CDD:320194	12/28 (43%)
		TM helix 6	404..434	CDD:320194	18/29 (62%)
		TM helix 7	444..469	CDD:320194	11/24 (46%)
Taar4	NP_001008499.1	7tmA_TAAR2_3_4	34..324	CDD:320437	109/326 (33%)
		TM helix 1	35..61	CDD:320437	12/24 (50%)
		TM helix 2	68..94	CDD:320437	7/25 (28%)
		TM helix 3	106..136	CDD:320437	15/29 (52%)
		TM helix 4	148..171	CDD:320437	9/22 (41%)
		Extracellular Loop 2 (ECL2). /evidence=ECO:0000250|UniProtKB:Q5QD04	175..188		5/18 (28%)
		TM helix 5	196..225	CDD:320437	12/28 (43%)
		TM helix 6	253..283	CDD:320437	18/30 (60%)
		TM helix 7	292..317	CDD:320437	11/24 (46%)