DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and Opn4

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_620215.1	Gene:	Opn4 / 192223	RGDID:	621701	Length:	474	Species:	Rattus norvegicus

Alignment Length:	463	Identity:	110/463 - (23%)
Similarity:	185/463 - (39%)	Gaps:	105/463 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SSASNSSTGGIALPLGTATPATHELNATQ--PFGGSGLNFNESGAGLSDHHHHQQHNPDEDWLDN 150
            :|..|.|   :.:.|.:.:|.|..|.|..  ||         ....:.||.|:.
  Rat    31 NSTQNIS---VRVQLLSVSPTTPGLQAAAWVPF---------PTVDVPDHAHYT----------- 72

  Fly   151 IVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQV 215
                 ...|:||:.:..:.|||.||.:..|.|.||...|..:::||::|.:::.......|:..:
  Rat    73 -----LGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMLIINLAVSDFLMSFTQAPVFFASSL 132

  Fly   216 TGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWIS 280
            ..:|.|....|..:......|...|::.|..|::|||..|.:||......:||...::||..|:.
  Rat   133 YKKWLFGETGCKFYAFCGAVFGIVSMITLTAIAMDRYLVITRPLATIGMRSKRRTALVLLGVWLY 197

  Fly   281 PALLSFLPIFIGWYTTPQHQQFVIQN-PTQCSF------VVNKYYAVISSSISFWIPCTIMIFTY 338
             ||...||.|.||      ..:|.:. .|.||:      .:.:.|.::.....|::|..|:||.|
  Rat   198 -ALAWSLPPFFGW------SAYVPEGLLTSCSWDYVTFTPLVRAYTMLLFCFVFFLPLLIIIFCY 255

  Fly   339 LAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKM 403
            :.|||                      :::.:|.|..|.|.|             |.:.:...::
  Rat   256 IFIFR----------------------AIRETGRACEGCGES-------------PLRRRQWQRL 285

  Fly   404 KREHKAARTLGIIMGTFILCWLPF-------FLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLN 461
            :.|.|.|:...|::..|:|.|.|:       |..|:..:|.....||.::...       ::..|
  Rat   286 QSEWKMAKVALIVILLFVLSWAPYSTVALVGFAGYSHILTPYMSSVPAVIAKA-------SAIHN 343

  Fly   462 PLIYAYFNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRS--SLRYDQRAKSVYS--ESYLNST 522
            |:|||..:..:|.|....|.||        .:.|.:..:||  ||.|....:|..|  .|.|:..
  Rat   344 PIIYAITHPKYRAAIAQHLPCL--------GVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWI 400

  Fly   523 TPSHRRQS 530
            :...|::|
  Rat   401 SGQKRQES 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	50/184 (27%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	74/308 (24%)
Opn4	NP_620215.1	7tm_4	78..>245	CDD:304433	46/173 (27%)
		7tm_1	87..347	CDD:278431	74/308 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	428..474
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910