DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and Ptger3

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	NP_001346674.1	Gene:	Ptger3 / 19218	MGIID:	97795	Length:	366	Species:	Mus musculus

Alignment Length:	390	Identity:	75/390 - (19%)
Similarity:	133/390 - (34%)	Gaps:	103/390 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 HHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVI--TNYFVVS---L 195
            |..:.|:......|:...|..||.:.:::...: ||.|.::.|.|..:.|..  ...|::.   |
Mouse     9 HSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFV-GNALAMLLVSRSYRRRESKRKKSFLLCIGWL 72

  Fly   196 AMADIMVAIMAMTFNFSVQVT-GRW---NFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIV 256
            |:.|::..::.......|.:: .||   :.|..||..:......|..:|:|....::|:|..||.
Mouse    73 ALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIR 137

  Fly   257 KPLKYPISMTKRVVGIMLLNTWISPALLSFLPIF-IGWYTTPQHQQFVIQNP-TQCSFVVNKYYA 319
            .|..|...|..|....:||..|:|....:.||:. :|.|:        :|.| |.|
Mouse   138 APHWYASHMKTRATRAVLLGVWLSVLAFALLPVLGVGRYS--------VQWPGTWC--------- 185

  Fly   320 VISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLT 384
                              :::.....|..:               |:.:|...|.:.:.:...|.
Mouse   186 ------------------FISTGPAGNETD---------------PAREPGSVAFASAFACLGLL 217

  Fly   385 LHEVEQEHTPTKDKHLIKMKREHKAA-----------------RTLGIIMGTFILCWLPFFLWYT 432
            ...|.........|.|:...|. |||                 :.:| ||....:||.|..:...
Mouse   218 ALVVTFACNLATIKALVSRCRA-KAAVSQSSAQWGRITTETAIQLMG-IMCVLSVCWSPLLIMML 280

  Fly   433 L----SMTCEECQVP--------DIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLCLFC 485
            .    .|:.|:|:..        ..::::.  :...|..|:|.:|.        ..|..||..||
Mouse   281 KMIFNQMSVEQCKTQMGKEKECNSFLIAVR--LASLNQILDPWVYL--------LLRKILLRKFC 335

Fly 486 485
Mouse 336 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	39/188 (21%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	63/334 (19%)
Ptger3	NP_001346674.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		2/12 (17%)
		7tm_GPCRs	26..335	CDD:333717	70/371 (19%)
		TM helix 1	28..52	CDD:320095	6/24 (25%)
		TM helix 2	66..88	CDD:320095	3/21 (14%)
		TM helix 3	108..130	CDD:320095	3/21 (14%)
		TM helix 4	153..169	CDD:320095	4/15 (27%)
		TM helix 5	204..227	CDD:320095	3/22 (14%)
		TM helix 6	255..280	CDD:320095	6/25 (24%)
		TM helix 7	302..327	CDD:320095	4/34 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910