Protein Alignment Octbeta2R and ser-2

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001024339.1
• Gene: ser-2 / 182110
• WormBaseID: WBGene00004777
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 393
• Identity: 120/393 - (30%)
• Similarity: 186/393 - (47%)
• Gaps: 75/393 - (19%)

  Fly   154 VFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVT-- 216
            |......|:||...:.||.||:::|...|.|:.:.|||:||||.:|:.|||..|..:.   ||
 Worm    58 VLGTITYLVIIAMTVVGNTLVVVAVFSYRPLKKVQNYFLVSLAASDLAVAIFVMPLHV---VTFL 119

  Fly   217 --GRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWI 279
              |:|.....:|..:.:.|:...|:|||:||.|::|||:||..|:.|....|.:.|.|:::..||
 Worm   120 AGGKWLLGVTVCQFFTTADILLCTSSILNLCAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWI 184

  Fly   280 SPALLSFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFRE 344
            ...|:|..|| |||....::..     ...|.....|.:.|.|::.||::|..:|:..|:.||..
 Worm   185 LSMLISVPPI-IGWNNWQENMM-----EDSCGLSTEKAFVVFSAAGSFFLPLLVMVVVYVKIFIS 243

  Fly   345 ANR-----QEKQLMMRHGNA--------MLMHRPSMQPS------GE-----ALSGSGSSKTLTL 385
            |.:     :.:..:||..||        |.:.|.|::.:      ||     ...|..:..||..
 Worm   244 ARQRIRTNRGRSALMRIQNAEGDDDYRKMSIKRASVESARTSSRVGEKTPLVIADGQTTVTTLAA 308

  Fly   386 HEVEQEHTPTKD---KHL---------IKMK------------------------REHKAARTLG 414
            |..:....| ||   ||:         :|:|                        :|.:||:|:.
 Worm   309 HSTDGGSLP-KDETTKHMKYHNNGSCKVKVKDVKEDEGNPNPTAVLRKREKISVAKEKRAAKTIA 372

  Fly   415 IIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNT 479
            :|:..|..||||||:.|.:...||.|::...|.....|:||.||:|||.:|...|.:||.||:.
 Worm   373 VIIFVFSFCWLPFFVAYVIRPFCETCKLHAKVEQAFTWLGYINSSLNPFLYGILNLEFRRAFKK- 436

  Fly   480 LLC 482
            :||
 Worm   437 ILC 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	115/384 (30%)
		TM helix 1	155..181	CDD:320194	8/25 (32%)
		TM helix 2	188..214	CDD:320194	12/25 (48%)
		TM helix 3	226..256	CDD:320194	13/29 (45%)
		TM helix 4	268..291	CDD:320194	8/22 (36%)
		TM helix 5	315..344	CDD:320194	10/28 (36%)
		TM helix 6	404..434	CDD:320194	14/53 (26%)
		TM helix 7	444..469	CDD:320194	10/24 (42%)
ser-2	NP_001024339.1	7tmA_tyramine_octopamine_R-like	58..434	CDD:320188	116/385 (30%)
		TM helix 1	59..85	CDD:320188	8/25 (32%)
		TM helix 2	92..118	CDD:320188	13/28 (46%)
		TM helix 3	131..161	CDD:320188	13/29 (45%)
		TM helix 4	173..196	CDD:320188	8/23 (35%)
		TM helix 5	214..243	CDD:320188	10/28 (36%)
		TM helix 6	362..392	CDD:320188	13/29 (45%)
		TM helix 7	402..427	CDD:320188	10/24 (42%)