Protein Alignment Octbeta2R and DRD5

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_000789.1
• Gene: DRD5 / 1816
• HGNCID: 3026
• Length: 477
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 140/422 - (33%)
• Similarity: 209/422 - (49%)
• Gaps: 75/422 - (17%)

  Fly   154 VFKAFVMLLIIIAAICGNLLVIISVMRVRKLRV-ITNYFVVSLAMADIMVAIMAMTFNFSVQVTG 217
            |..|.::.|:||..:.||:||..:::|.|.||. :||.|:||||::|:.||::.|.:....:|.|
Human    41 VVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAG 105

  Fly   218 RWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPA 282
            .|.|..| ||:|.:.|:..||||||:||.||||||:||.:|.:|...||:|:..:|:...|....
Human   106 YWPFGAF-CDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSI 169

  Fly   283 LLSFLPIFIGWYT------------------TPQHQQF--VIQNPTQCSFVVNKYYAVISSSISF 327
            |:||:|:.:.|:.                  ||..:.|  ...|...|...:|:.||:.||.|||
Human   170 LISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISF 234

  Fly   328 WIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEH 392
            :||..|||.||..|:|.|..|.:::            .|::.:.|......||...
Human   235 YIPVAIMIVTYTRIYRIAQVQIRRI------------SSLERAAEHAQSCRSSAAC--------- 278

  Fly   393 TPTKDKHL-IKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCE----------ECQVPDIV 446
              ..|..| ..:|:|.|..:||.:|||.|:.||||||:...:...|.          .| |.:..
Human   279 --APDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPC-VSETT 340

  Fly   447 VSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLCL-FCNWWKDRHLPLD-IDIRRSSLRYDQ- 508
            ..:..|.|:.||:|||:||| ||.||::.|...|.|. ||:     ..|:: ::|....:.|:|
Human   341 FDVFVWFGWANSSLNPVIYA-FNADFQKVFAQLLGCSHFCS-----RTPVETVNISNELISYNQD 399

  Fly   509 -----RAKSVYSESYLNSTTPSHRRQSQMVDN 535
                 ...:.|.....|:.||.:|.    |||
Human   400 IVFHKEIAAAYIHMMPNAVTPGNRE----VDN 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	78/198 (39%)
		7tm_1	170..465	CDD:278431	111/326 (34%)
DRD5	NP_000789.1	7tm_1	57..359	CDD:278431	111/326 (34%)
		7tm_4	<123..>175	CDD:304433	26/51 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.970