Protein Alignment Octbeta2R and dop-6

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001359889.1
• Gene: dop-6 / 180706
• WormBaseID: WBGene00016037
• Length: 692
• Species: Caenorhabditis elegans
• Alignment Length: 719
• Identity: 154/719 - (21%)
• Similarity: 241/719 - (33%)
• Gaps: 296/719 - (41%)

  Fly   145 EDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTF 209
            ||.|....|.:  .|:.::.:..|.|||:|:.:|...:.|:..||:.:|||||||::|....|.|
 Worm    16 EDELLQPEWAY--LVLSIVPLVCILGNLMVVAAVWTTKSLQTPTNHLLVSLAMADLIVGAFVMPF 78

  Fly   210 NFSVQVTG-RWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIM 273
            :..:.|.. .|:...|:|..:..|||..||:||:||..||:||..|..||.:|.....::.|.:.
 Worm    79 SIYLSVNRLHWHLPLFVCYFYCVLDVAASTSSIIHLVLISIDRLVAATKPAEYKTVKHRKRVYLA 143

  Fly   274 LLNTWISPALLSFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTY 338
            :..|||....|| ||:..|:.|...: ..||::  .|. :.|..|.:.||..:|::||.||||||
 Worm   144 IAITWIFSIALS-LPLGTGFNTRTSY-FLVIEH--HCG-IYNPIYMLGSSIFAFYLPCLIMIFTY 203

  Fly   339 LAIFREANRQ---------------------------------------------EKQLMMRHGN 358
            ..||....::                                             ||.|:.:...
 Worm   204 GYIFYTLRKRLRAIQLQEMAGGQFLGFGADVSNITTSAIQSVIGIAPKNRNMITWEKPLLKKIEE 268

  Fly   359 AMLMHRPSMQPSG--------EAL--SGSGSSKTLTLHE-------------------------- 387
            ....|..|:..|.        ||:  |.|||.:..|:.|
 Worm   269 TAAEHASSLNDSEREQLQTILEAVHPSSSGSQENTTIEEDPDRPPSVLLEAVTLKCEIDTSGPIL 333

  Fly   388 --------------------------------------VEQEHTP-----------TKDKHLIK- 402
                                                  ....|.|           :|..|.:|
 Worm   334 ELPRPTYTKNMSRRFSDAVNSISSRGRMKSVSFGTSRKRRHSHQPQGNREVVTSEESKKLHSLKP 398

  Fly   403 ----------------------------------------------------------------- 402
                                                                             
 Worm   399 PLVEKRKMRRLSEMISDWERPSRSSISNMYLYARRESVYIARKKLAGLKDWALDLLAKLKSKQGM 463

  Fly   403 -MKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSI--------LFW---IGY 455
             ::||.:|.:.:..:|..|::||||||   ||:|    .::..::.::        ..|   :||
 Worm   464 AIRRETRATKLVATVMVVFLVCWLPFF---TLNM----IKIYKLIFNVWSADLEIWFHWFTALGY 521

  Fly   456 FNSTLNPLIYAYFNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRSSLRYDQRAKS-------- 512
            .||:||..||:..|..||.:||..|                 ..||||.|  ||.||
 Worm   522 LNSSLNFFIYSTINPKFRHSFRRLL-----------------GFRRSSRR--QREKSWMLPPRDS 567

  Fly   513 ------------VYSESYLNSTT---PSHRRQSQMVDNLXYRDEALLTPIAQQQQRLAAGGSRLG 562
                        ...:|.|..|:   |.:.|:..|     .:.|.::..|:..:..::|||:
 Worm   568 SRGPAKCGCGFHKIVKSPLRKTSSAGPMNNRKISM-----QKPEIVIDEISPNRISISAGGN--- 624

  Fly   563 GQLAAAAKDGRESKDAKDTGKDAGKGKSNVDCLAGDDVQEI-QIEIPMEYINKWNKNNNAAASTA 626
                   ...|.|.|               ||:.....:.| .|.:|.:..|...:.:..:.|:|
 Worm   625 -------TTFRRSSD---------------DCIRRSSSEIIGGITLPSQSSNDKRRGSGMSNSSA 667

  Fly   627 SSHV 630
            |.|:
 Worm   668 SLHI 671

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	66/178 (37%)
		7tm_1	170..465	CDD:278431	107/503 (21%)
dop-6	NP_001359889.1	7tmA_amine_R-like	24..>217	CDD:320098	70/199 (35%)
		TM helix 1	25..49	CDD:320098	7/25 (28%)
		TM helix 2	58..80	CDD:320098	11/21 (52%)
		TM helix 3	97..119	CDD:320098	10/21 (48%)
		TM helix 4	142..158	CDD:320098	6/16 (38%)
		TM helix 5	181..204	CDD:320098	11/22 (50%)
		7tm_GPCRs	<464..542	CDD:391938	26/84 (31%)
		TM helix 6	466..496	CDD:341315	14/36 (39%)
		TM helix 7	513..535	CDD:341315	9/21 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910