Protein Alignment Octbeta2R and tkr-3

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 110/459 - (23%)
• Similarity: 180/459 - (39%)
• Gaps: 102/459 - (22%)

  Fly   104 TATPATHELNATQPFGGSGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIA-- 166
            :||.:......|...||:|:......|.||......:..|    ::.|:|     .||..|||
 Worm     4 SATDSILASTITTVIGGAGVLAEAGEAELSGDDDFYELTP----VELIIW-----CMLYAIIAFM 59

  Fly   167 AICGNLLVI-ISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWN 230
            |:.|||||: |::.|:| :|.||.||:::|..||:...|.|:.|.|...:...|.....||.:..
 Worm    60 AVVGNLLVLYITLFRLR-VRSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLPRSLCRIVP 123

  Fly   231 SLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLP--IFIGW 293
            .::....|.|:..|...:|..:..:.  ......|:.|.....:|..||...|:| ||  :|...
 Worm   124 YVETVALTVSVFTLVTSAVHEFRTMF--FSKCSQMSPRSAKRCVLLIWIMAVLVS-LPHGLFHNT 185

  Fly   294 YTTPQHQQFVIQNPTQCSFVVN-----KYYAVISSSISFWIPCTIM--IFTYLAI------FREA 345
            |..|......|   .||..|..     |.|.|....|.:::|..|:  .:|.:|:      ....
 Worm   186 YEFPDDNNTSI---VQCLPVYPDAGWWKTYNVYLVIIQYFVPMIILDTAYTMIAVKIWSLSQSRV 247

  Fly   346 NRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAA 410
            ...|.::..:..:.:.|..|:.|.|                                     :..
 Worm   248 ELDETKMATQKISVVSMVSPNTQLS-------------------------------------QLM 275

  Fly   411 RTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDI----VVSILF----WIGYFNSTLNPLIYAY 467
            |||.|::..|.|||.|...:..|:    |.: |:|    .::::|    |:...||.|||:||..
 Worm   276 RTLIIVVACFSLCWFPLETYLLLN----ELK-PEINGWKYINLVFFFSHWLAMSNSCLNPIIYGL 335

  Fly   468 FNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRSSLRYDQRAKSVYSESYLNSTTPSHRRQ--S 530
            :|..:.|.:|.....:.|.|.:.:.|.       .|::.::|         .||:.....:|  .
 Worm   336 YNTKYNEEYRRLFRQIGCIWQRQKSLD-------DSMKPERR---------WNSSNDCQDQQEID 384

  Fly   531 QMVD 534
            |:||
 Worm   385 QIVD 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	55/195 (28%)
		7tm_1	170..465	CDD:278431	76/318 (24%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:391938	88/350 (25%)
		TM helix 1	48..74	CDD:341315	13/30 (43%)
		TM helix 2	81..106	CDD:341315	10/24 (42%)
		TM helix 3	119..149	CDD:341315	5/29 (17%)
		TM helix 4	160..181	CDD:341315	7/21 (33%)
		TM helix 5	209..238	CDD:341315	8/28 (29%)
		TM helix 6	254..299	CDD:341315	13/81 (16%)
		TM helix 7	312..337	CDD:341315	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910