Protein Alignment Octbeta2R and npr-34

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_497057.2
• Gene: npr-34 / 175131
• WormBaseID: WBGene00013187
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 103/512 - (20%)
• Similarity: 183/512 - (35%)
• Gaps: 136/512 - (26%)

  Fly   158 FVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFS 222
            |:.|.:.:....||.:||..|.|.:::|.:||.|:.||:.||:.:....:...|...::..|:..
 Worm    77 FLYLTVFLVGTIGNSMVIFVVNRFKRMRNVTNIFLASLSTADLCLIWFCVPIMFMKYMSHTWSMG 141

  Fly   223 PFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLK----YPISMTKRVVGIMLLNTWISPAL 283
            .|.|...:.:..:....|:|.:..||.:|:.||..|::    ..|...|:|:    |..|:|.|:
 Worm   142 RFACYSVHYIQQFTCFCSVLTMTMISFERFLAIAYPMRNIWFSSIGRAKKVI----LLIWMSSAV 202

  Fly   284 LS--------------------------FLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVIS 322
            |:                          |...|:|:..|.                :||.||:..
 Worm   203 LAVPTAVRMDYETNLSLSGQRVHWCRRRFPAQFLGYPRTS----------------LNKAYAMYQ 251

  Fly   323 SSISFWIPCTIMIFTYLAIFREANRQEK------QLMMRHGNAMLMHRPSMQPSGEALSGSGSS- 380
            ..:....|...|...|..:.....:..|      |.|:....|          :.:|::.||.|
 Worm   252 LLLLIIFPVLTMSICYARVSAIVYKSSKDRVILSQAMVAFSKA----------ATDAVTFSGYSA 306

  Fly   381 --KTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVP 443
              ...|...::..:|..|.....:..|..:|.:...:.|...|:|      .||:      |.:|
 Worm   307 IPMITTSRNLKTANTTIKSYSNHRNNRVAEANKKQIVQMLISIVC------MYTV------CWLP 359

  Fly   444 DIVVSILFWIGY----------------FN------STLNPLIYAYFNRDFREAFRNTLLCLFCN 486
            .||..:|...||                ||      |.:||::||:.:::||..|:.....:
 Worm   360 TIVDELLTSFGYICRTSNTQTLKHMRMGFNALTYCQSCINPILYAFISQNFRSTFKTAYSRM--- 421

  Fly   487 WWKDRHLPLDIDIRRSSLRYDQRAKS---VYSESYLNSTTPSHRRQSQMVDNLXYRDEALLTP-- 546
                          :|.|:..:..:|   ..|.:.:.||...||......:.|.....:::||
 Worm   422 --------------KSRLQGVEEMRSRMGSCSSASMMSTRNQHRIYGSSFNTLTVPGRSMITPNM 472

  Fly   547 ---IAQ-------QQQRLAAGGSRLGGQLAAAAKDGRESKDAKDTGKDAGKGKSNVD 593
               ::|       .|.......|.:.|...:.....| .:...|...|:|:.:|..|
 Worm   473 SRDVSQLSLCRPTSQMSFCRPKSPMAGDSPSTFMRHR-PRSPTDVSHDSGRPRSPTD 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	45/207 (22%)
		7tm_1	170..465	CDD:278431	75/355 (21%)
npr-34	NP_497057.2	7tmA_GPRnna14-like	75..414	CDD:320132	81/378 (21%)
		TM helix 1	75..99	CDD:320132	7/21 (33%)
		TM helix 2	108..130	CDD:320132	6/21 (29%)
		TM helix 3	146..168	CDD:320132	3/21 (14%)
		TM helix 4	191..207	CDD:320132	6/19 (32%)
		TM helix 5	245..268	CDD:320132	5/22 (23%)
		TM helix 6	340..365	CDD:320132	9/36 (25%)
		TM helix 7	382..407	CDD:320132	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910