Protein Alignment Octbeta2R and ADORA1

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: NP_000665.1
• Gene: ADORA1 / 134
• HGNCID: 262
• Length: 326
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 91/370 - (24%)
• Similarity: 155/370 - (41%)
• Gaps: 94/370 - (25%)

  Fly   159 VMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSP 223
            :.:||.:.::.||:|||.:|...:.||..|..|:||||:||  ||:.|:....::.:    |..|
Human    15 IEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVAD--VAVGALVIPLAILI----NIGP 73

  Fly   224 FLCDLWNSLDVYFST-------------ASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLL 275
                     ..||.|             :|||.|..|:||||..:..||:|.:.:|.|...:.:.
Human    74 ---------QTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIA 129

  Fly   276 NTWISPALLSFLPIFIGWYTTPQHQQFVIQNPT------QCSF--VVNKYYAVISSSISFWI--P 330
            ..||...::...|:| ||......::....|.:      :|.|  |::..| ::..:...|:  |
Human   130 GCWILSFVVGLTPMF-GWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEY-MVYFNFFVWVLPP 192

  Fly   331 CTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPT 395
            ..:|:..||.:|....:|             :::.....||:.....|
Human   193 LLLMVLIYLEVFYLIRKQ-------------LNKKVSASSGDPQKYYG----------------- 227

  Fly   396 KDKHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTL 460
                     :|.|.|::|.:|:..|.|.|||..:...:::.|..|..|.|:..|..::.:.||.:
Human   228 ---------KELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAM 283

  Fly   461 NPLIYAYFNRDFREAFRNTLLCLFCNWWKDRHL------PLDIDI 499
            ||::||:..:.||..|...        |.| |.      |:|.|:
Human   284 NPIVYAFRIQKFRVTFLKI--------WND-HFRCQPAPPIDEDL 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	54/200 (27%)
		7tm_1	170..465	CDD:278431	78/317 (25%)
ADORA1	NP_000665.1	7tm_4	18..>137	CDD:304433	42/133 (32%)
		7tm_1	26..288	CDD:278431	78/317 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910