DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Octbeta2R and GPRVPR1

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_321100.4	Gene:	GPRVPR1 / 1281161	VectorBaseID:	AGAP001962	Length:	605	Species:	Anopheles gambiae

Alignment Length:	508	Identity:	113/508 - (22%)
Similarity:	190/508 - (37%)	Gaps:	129/508 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PPRQRHRNRT------SA---------ARIRKRPKCCCGDGGSGNQAEQPGGIVSNPISYGQSLT 60
            |||...||.|      ||         .|.|.:.....|..||..|      |...|:.:.
Mosquito    87 PPRWTIRNDTFRPFQQSAKLAGGGGLNMRFRDQTDTYTGSAGSSTQ------IAPFPLDHS---- 141

  Fly    61 TLARVTAAALTTAAMLH---TTNALAATGSSSASNSSTGGIALPLGTATPATHEL----NATQPF 118
                 :||...:|...|   ....|.:.||..|.|...|      ...|||..::    .||...
Mosquito   142 -----SAAIGESADAAHGSSVAGGLGSVGSFVAVNDVIG------MNITPALSQVLLAPPATSAG 195

  Fly   119 GGSGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFK----AFVMLLIIIAAICGNLLVIISVM 179
            .|:.:....:||...|:....:.       .|..:.::    ||:.:|..: .:.||..|::::|
Mosquito   196 SGASIIAAVNGAAADDNGTRGEE-------INSFYFYETEQFAFLWVLFTV-IVLGNSAVLVTLM 252

  Fly   180 --RVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVYFSTASIL 242
              |.||.|:  |:|:..||:||:.|.::.:..:...::|..|......|.....:.|..:.||..
Mosquito   253 LNRTRKSRM--NFFIKQLAIADLCVGLLNVLTDIIWRITVVWRAGNAACKAIRFVQVCVTYASTY 315

  Fly   243 HLCCISVDRYYAIVKPLKYP--ISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQQFVIQ 305
            .|..:|:|||.||..|:.:.  .|..:::|..    .| |.::|..|||      |..:::.:||
Mosquito   316 VLVALSIDRYDAITHPMNFSGCWSRARKLVAA----AW-SFSILFSLPI------TYFYEERLIQ 369

  Fly   306 NPTQC------SFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHR 364
            ...||      ::....|...:|.|: |.:|..|:...|..|.|..
Mosquito   370 GKMQCWIDLVEAWRWQLYMCWVSGSL-FVVPALIISACYAVIVRTI------------------- 414

  Fly   365 PSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKD--------KHLIKMKREHKAARTLGIIMGTFI 421
                          .:|...|..:::.|....|        :.:|...:......|:.|:: .|:
Mosquito   415 --------------WAKGTILGPIDRTHNGMADLATRRASSRGIIPRAKVKTVKMTIVIVI-VFV 464

  Fly   422 LCWLPFFLWYTLSMTCEECQVPD-----IVVSILFWIGYFNSTLNPLIYAYFN 469
            |||.|:.::..|.:.   .|:|.     .:.:.:..:...||..|||||..|:
Mosquito   465 LCWSPYIIFDLLQVF---GQIPATQTNVAIATFIQSLAPLNSAANPLIYCLFS 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	49/187 (26%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	71/317 (22%)
GPRVPR1	XP_321100.4	7tm_4	236..524	CDD:304433	75/331 (23%)
GPRVPR1	XP_321100.4	7tm_1	243..510	CDD:278431	71/317 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910