DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and LOC105946838

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_017947772.1	Gene:	LOC105946838 / 105946838	-ID:	-	Length:	352	Species:	Xenopus tropicalis

Alignment Length:	348	Identity:	69/348 - (19%)
Similarity:	140/348 - (40%)	Gaps:	101/348 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 FVMLLIIIA---AICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRW 219
            |:.:|..:|   .:.||:|||..::..:|||..|:.::.::|::|::. ::::.| .:..:...|
Frog    34 FLPVLYCLAFTFGLVGNILVIFVLVYCKKLRTTTDVYLFNMAVSDLLF-VVSLPF-IAYTIINEW 96

  Fly   220 NFSPFLCDLWNSLDVYF--STASILHLCCISVDRYYAIVKPLKYPISMTKRVVG---IMLLNTWI 279
            .|...:|.:.::  :||  ..:||..:..:|||||:|||..:   .::..|.|.   |:.:..|:
Frog    97 IFGNIMCKILST--IYFVGFFSSIFFITVMSVDRYFAIVHVV---FALRVRNVRWGLIVSIVVWV 156

  Fly   280 SPALLSFLPIFIGWYTTPQ---HQQFVIQNPTQCSF---VVNK-----YYAVISSSISFWIPCTI 333
            ....:|          ||.   |:..:..|.|:|..   .:|:     :.:::.:.....||..|
Frog   157 LALSIS----------TPNFKFHEIVMTGNYTECVLSYPEINRQNWKIFCSLLINIFGLVIPLFI 211

  Fly   334 MIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDK 398
            ::|:||.|.:                      ::|.|
Frog   212 LLFSYLHIIK----------------------TLQNS---------------------------- 226

  Fly   399 HLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLS---------MTCEECQVPDIVVSILFWIG 454
               |.|::..|.|.:.|:...|.:.|.|:.:...|:         :..::.|.   ...:...:.
Frog   227 ---KCKQKRCAIRLILIVGIVFFIFWTPYNIVVFLNILKTSGAVDLETDQLQT---AADVTHTLS 285

  Fly   455 YFNSTLNPLIYAYFNRDFREAFR 477
            ..:..|||:||.:....||...|
Frog   286 LVHCCLNPIIYTFAGEKFRGYLR 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	46/196 (23%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	61/319 (19%)
LOC105946838	XP_017947772.1	7tmA_Chemokine_R	33..307	CDD:341319	68/345 (20%)
		TM helix 1	33..60	CDD:341319	8/25 (32%)
		TM helix 2	67..92	CDD:341319	4/26 (15%)
		TM helix 3	103..133	CDD:341319	11/31 (35%)
		TM helix 4	147..167	CDD:341319	5/29 (17%)
		TM helix 5	193..222	CDD:341319	7/50 (14%)
		TM helix 6	229..259	CDD:341319	7/29 (24%)
		TM helix 7	275..300	CDD:341319	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910