DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and htr4

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_009289337.1	Gene:	htr4 / 101882850	ZFINID:	ZDB-GENE-160114-31	Length:	423	Species:	Danio rerio

Alignment Length:	327	Identity:	124/327 - (37%)
Similarity:	188/327 - (57%)	Gaps:	35/327 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 LIIIAAICGNLLVIISVMRVRKLRVI-TNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFL 225
            |:::.::.|||||:::|.:.|:||.| ||||:||||.||::|:::.|.|.....:...|.:....
Zfish    68 LVMLMSVLGNLLVMVAVCKDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELIHQNWIYGETF 132

  Fly   226 CDLWNSLDVYFSTASILHLCCISVDRYYAI-VKPLKYPISMTKRVVGIMLLNTWISPALLSFLPI 289
            |.:..||||..:|||||||||||:|||||| .:||.|...||...|.:|:...||.|.::|||||
Zfish   133 CLVRTSLDVLLTTASILHLCCISLDRYYAICCQPLVYRNKMTPLRVTLMIGGCWIIPTVISFLPI 197

  Fly   290 FIGWYTTP----QHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEK 350
            ..||.:..    ..::.:..|.|.|.|:|||.||:..|.::|::|..:|:..|..|:..|....:
Zfish   198 MQGWNSIGIKDLIDKRKISGNSTVCVFMVNKPYALTCSVVAFYLPLVLMVLAYQRIYVTAREHAR 262

  Fly   351 QLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGI 415
            |:.|            :|.:|    |:|::.:.   :.::.|         :|:.|.|||:||.|
Zfish   263 QISM------------LQRAG----GAGNADSA---DHQRNH---------RMRTETKAAKTLCI 299

  Fly   416 IMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTL 480
            |||.|.|||.|||:...:.... :..||:.:.:...|:||.||.|||::||:.|:.||.||...|
Zfish   300 IMGCFCLCWAPFFITNVVDPFI-DYSVPEQLWAACLWLGYINSMLNPILYAFLNKSFRRAFLIIL 363

  Fly   481 LC 482
            .|
Zfish   364 CC 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	77/183 (42%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	114/300 (38%)
htr4	XP_009289337.1	7tm_4	68..>198	CDD:304433	61/129 (47%)
		7tm_1	76..348	CDD:278431	114/300 (38%)
		TAS2R	<172..365	CDD:283059	73/221 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D328277at33208
OrthoFinder	1	1.000	-	-		FOG0005484
OrthoInspector	1	1.000	-	-		otm26202
orthoMCL	1	0.900	-	-		OOG6_107218
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.820