Protein Alignment Octbeta2R and LOC100498398

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_002931741.2
• Gene: LOC100498398 / 100498398
• -ID: -
• Length: 456
• Species: Xenopus tropicalis
• Alignment Length: 429
• Identity: 115/429 - (26%)
• Similarity: 193/429 - (44%)
• Gaps: 89/429 - (20%)

  Fly   126 NESGAGLSDH--HHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVIT 188
            |...|||::.  .|:.|       ..:.|.:..|.:|.|:::|.:.||.|||::.:..:.||...
 Frog    33 NACAAGLAEEQLQHYGQ-------FSSSVSIILAVLMALMVLATVLGNALVILAFVVEKGLRTQG 90

  Fly   189 NYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYY 253
            |:|.::||:||.:|....:.......:||:|.|...||.||..:|....|||:.::..||.||:.
 Frog    91 NFFFLNLAIADFLVGGFCIPLYIPYVLTGQWKFGKGLCKLWLVMDYLLCTASVFNIVLISYDRFI 155

  Fly   254 AIVKPLKYPI--SMTKRVVGIMLLNTWISPALLSFLPIFIGW----YTT--PQHQQFVIQNPTQC 310
            ::.|.:.|..  .||:..| :.:|..|:: |.|.:.|..|.|    .||  |:.:.:|
 Frog   156 SVTKAVSYRAQKGMTRNAV-LKMLIVWVA-AFLLYGPAIITWEYIARTTILPEGECYV------- 211

  Fly   311 SFVVNKYYAVISSSISFWIPCTIMIFTYLAIF-----REANRQEKQLM-----------MRHGNA 359
            .|..|.|:.:|:|:|.|:.|...:.:..|:|:     |...|.|:...           .|..:.
 Frog   212 EFYYNWYFLMIASTIEFFTPFISVTYFNLSIYINIKRRTMMRNEEMAQGQEHCELTFQGKRKEHL 276

  Fly   360 MLMHRPSMQPSGEA------LS-------GSGS----SKTLTLH--------EVEQEHTPTKD-- 397
            :...:|:.:|.|||      ||       |:|:    |..|.|:        :||.....::|
 Frog   277 IFFVKPADRPYGEAKKQGGTLSPAMPSAVGNGAQELESPMLDLNINQDLPPLQVEVSAKKSQDCF 341

  Fly   398 -------------------KHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVP 443
                               .:..::.|:.:.|::|.||:..|.|||.|:.|...:...|....|.
 Frog   342 YKSAENACSNMRPDMASSIANRFRLSRDKRVAKSLAIIVCVFGLCWAPYTLLMIIRAACHGRCVQ 406

  Fly   444 DIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLC 482
            |.:..|.||:.:.||.:||::|...:..||:||.. |||
 Frog   407 DYLYEISFWLLWLNSAINPVLYPLCHMSFRKAFMK-LLC 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	56/185 (30%)
		7tm_1	170..465	CDD:278431	96/364 (26%)
LOC100498398	XP_002931741.2	7tmA_Histamine_H3R	56..439	CDD:320423	103/391 (26%)
		TM helix 1	57..83	CDD:320423	9/25 (36%)
		TM helix 2	90..117	CDD:320423	7/26 (27%)
		TM helix 3	128..158	CDD:320423	11/29 (38%)
		TM helix 4	173..191	CDD:320423	5/19 (26%)
		TM helix 5	216..246	CDD:320423	9/29 (31%)
		TM helix 6	367..397	CDD:320423	11/29 (38%)
		TM helix 7	407..432	CDD:320423	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910