Protein Alignment Octbeta2R and htr7

DIOPT Version :10

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_031762460.1
• Gene: htr7 / 100494876
• XenbaseID: XB-GENE-1013674
• Length: 440
• Species: Xenopus tropicalis
• Alignment Length: 345
• Identity: 130/345 - (37%)
• Similarity: 186/345 - (53%)
• Gaps: 42/345 - (12%)

  Fly   159 VMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVT----GRW 219
            ::.||.:..|.||.||:|||..|:|||..:||.:||||:||:.|||..|.|   |.||    |.|
 Frog    84 ILSLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAIAVMPF---VSVTDLIGGEW 145

  Fly   220 NFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALL 284
            .|....|:::.::||...||||:.||.||:|||..|.:||.||:....|.:..|:|..|:..|.:
 Frog   146 IFGHVFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGRCMAKMILCVWLLSASI 210

  Fly   285 SFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQE 349
            :..|:| ||...       :.:...|....:..|.:.|::::|:||.::|:|.|..||:.|.|..
 Frog   211 TLPPLF-GWAQN-------VNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIFKAAKRSA 267

  Fly   350 KQLMMRHGNAMLMHR----PSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKD------KHLIKMK 404
            .:           |:    |..:.|...:|.:|:.||   |:..:|.|....      |::...|
 Frog   268 AK-----------HKFTGLPRPEESEGMISANGNVKT---HKESEECTNLSKLLRNDRKNISIFK 318

  Fly   405 REHKAARTLGIIMGTFILCWLPFFLWYTL-SMTC-EECQ-VPDIVVSILFWIGYFNSTLNPLIYA 466
            ||.|||.|||||:|.|.:|||||||..|. ...| .||. :|..:.....|:||.||.:||.|||
 Frog   319 REQKAATTLGIIVGAFTICWLPFFLLSTARPFICGTECSCIPLWLERTFLWLGYANSLINPFIYA 383

  Fly   467 YFNRDFREAFRNTLLCLFCN 486
            :||||.|..:||.|.|.:.|
 Frog   384 FFNRDLRTTYRNLLQCRYRN 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	125/333 (38%)
		TM helix 1	155..181	CDD:320194	10/21 (48%)
		TM helix 2	188..214	CDD:320194	13/25 (52%)
		TM helix 3	226..256	CDD:320194	14/29 (48%)
		TM helix 4	268..291	CDD:320194	6/22 (27%)
		TM helix 5	315..344	CDD:320194	10/28 (36%)
		TM helix 6	404..434	CDD:320194	21/30 (70%)
		TM helix 7	444..469	CDD:320194	10/24 (42%)
htr7	XP_031762460.1	7tmA_5-HT7	80..393	CDD:320452	125/333 (38%)
		TM helix 1	80..106	CDD:320452	10/21 (48%)
		TM helix 2	113..139	CDD:320452	15/28 (54%)
		TM helix 3	152..182	CDD:320452	14/29 (48%)
		TM helix 4	194..216	CDD:320452	6/21 (29%)
		TM helix 5	233..262	CDD:320452	10/28 (36%)
		TM helix 6	318..348	CDD:320452	21/29 (72%)
		TM helix 7	361..386	CDD:320452	10/24 (42%)