DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and ptgdr

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_031747558.1	Gene:	ptgdr / 100494338	XenbaseID:	XB-GENE-989130	Length:	338	Species:	Xenopus tropicalis

Alignment Length:	331	Identity:	69/331 - (20%)
Similarity:	119/331 - (35%)	Gaps:	81/331 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 LIIIAAICGNLLVIISVMRVRKLR--------VITNYFVVSLAMADIMVAIMAMTFNFS----VQ 214
            |:..|...|||:.:. ::.:.||.        |:.....|:..|...::..:.....|.    |.
Frog    24 LLFAAGFLGNLIALF-ILWLHKLHAKKTSVFYVLVTVLTVTNLMGKCLLCPVVQVAYFQNQSLVG 87

  Fly   215 VTGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWI 279
            :||..|    ||.::..|.::...|....|..::||.:.|:..|..|..::.|::..::.|..::
Frog    88 MTGNLN----LCKVFGFLMIFCGLAPTFILLAMAVDCWLALGYPFFYQENINKKLALLVSLILYV 148

  Fly   280 SPALLSFLPIF-IGWYT-----TPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIP-CTIMIFT 337
            .......||.| .|.|.     |....|...:..:..:...:..|..|...:...|. |.:||..
Frog   149 FCLGFCCLPFFGFGRYKQYCPGTWCFIQMTAEESSTSALAYSMLYGTIMGLLILAIVFCNLMIMK 213

  Fly   338 YL-AIFREANRQEKQLMMRHGNAMLMHRPS------MQPSGEALSGSGSSKTLTLHEVEQEHTPT 395
            .| .:::..|  ||.:            ||      .:|:|             :.|:|
Frog   214 NLYQMYKREN--EKGI------------PSANFPNQQEPAG-------------MEELE------ 245

  Fly   396 KDKHLIKMKREHKAARTLGIIMGTFILCWLPFFL-WYTLSMTCEECQVPDIVVSILFWIGYFNST 459
               |||          .|.|:...|..|..|... .|..:...|:.:..|:.|..|..:   |||
Frog   246 ---HLI----------LLAIMTVLFAACSFPLTARVYVGAFKGEKNEYADLTVLRLLSV---NST 294

  Fly   460 LNPLIY 465
            |:|.|:
Frog   295 LDPWIF 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	40/197 (20%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	66/321 (21%)
ptgdr	XP_031747558.1	7tmA_PGD2	16..312	CDD:320268	69/331 (21%)
		TM helix 1	18..42	CDD:320268	5/18 (28%)
		TM helix 2	54..76	CDD:320268	3/21 (14%)
		TM helix 3	96..118	CDD:320268	3/21 (14%)
		TM helix 4	141..157	CDD:320268	1/15 (7%)
		TM helix 5	186..209	CDD:320268	4/22 (18%)
		TM helix 6	247..269	CDD:320268	7/31 (23%)
		TM helix 7	279..304	CDD:320268	9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910