DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and opn8

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_004915005.1	Gene:	opn8 / 100493595	XenbaseID:	XB-GENE-983567	Length:	353	Species:	Xenopus tropicalis

Alignment Length:	347	Identity:	71/347 - (20%)
Similarity:	132/347 - (38%)	Gaps:	79/347 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 MLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFS-- 222
            :||:.|..:.||..|:.:.::........:...::||:||:.:||..    :.:.:...||.:
Frog    21 LLLVAILTVLGNCAVLATAVKCSSHLKAPDLLSINLAVADLGMAISM----YPLAIASAWNHAWL 81

  Fly   223 --PFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYP-ISMTKRVVGIMLLNTWISPALL 284
              ...|..:..:..:|..:|::.|..:::.| |.:....||. .::.|:.|.|:::..|:...|.
Frog    82 GGDASCLYYALMGFFFGVSSMMTLTVMAIIR-YRVTSSFKYSGCTIEKKAVCILIMCIWLYALLW 145

  Fly   285 SFLPIFIGW--YTTPQHQQFVIQNP----TQCSFVVNKYYAV---ISSSISFWIPCTI-----MI 335
            :.||: :||  |           .|    |.|:.....::..   .|..||.:|.|||     ::
Frog   146 AVLPL-LGWGRY-----------GPEPFGTSCTIAWGDFHHSSNGFSFIISMFILCTISPAVTIV 198

  Fly   336 FTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHL 400
            ..|                               ||.|..         ||:..|| ...:||..
Frog   199 VCY-------------------------------SGIAWK---------LHKAYQE-IKNQDKIP 222

  Fly   401 IKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIY 465
            ...|.|.|......::...|::.|.|:......|:......:|.:|..:.......::..||:||
Frog   223 NSTKVEKKLTLLAILVSFGFLISWTPYAAVSFWSLFHSSKYIPPVVSLLPCLFAKSSTAFNPMIY 287

  Fly   466 AYFNRDFREAFRNTLLCLFCNW 487
            ..|::.||...::...|  |.|
Frog   288 YAFSKTFRRKVKHLKCC--CGW 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	41/196 (21%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	60/313 (19%)
opn8	XP_004915005.1	7tmA_Opsin5_neuropsin	17..298	CDD:320202	68/334 (20%)
		TM helix 1	17..41	CDD:320202	6/19 (32%)
		TM helix 2	50..72	CDD:320202	6/25 (24%)
		TM helix 3	88..110	CDD:320202	3/21 (14%)
		TM helix 4	133..149	CDD:320202	3/15 (20%)
		TM helix 5	179..202	CDD:320202	8/53 (15%)
		TM helix 6	232..254	CDD:320202	3/21 (14%)
		TM helix 7	266..291	CDD:320202	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910