Protein Alignment Octbeta2R and adra1a

DIOPT Version :9

• Sequence 1: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Sequence 2: XP_002933012.2
• Gene: adra1a / 100492776
• XenbaseID: XB-GENE-6048410
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 433
• Identity: 134/433 - (30%)
• Similarity: 213/433 - (49%)
• Gaps: 86/433 - (19%)

  Fly   112 LNATQPFGGSGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLI----IIAAICGNL 172
            ||.|.|  |:.:|                             :.||.|:.:|    |...:.||:
 Frog    36 LNCTHP--GATIN-----------------------------ISKAIVVGVIFGVFITFGVLGNI 69

  Fly   173 LVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVYFS 237
            |||:||...|.|:.:|:||:.:||:||:::..|.:.|:.:.::.|.|.|....|::|.::||...
 Frog    70 LVILSVACHRHLQTVTHYFIANLAVADLLLMSMVLPFSATFEIQGYWLFGRIFCNIWAAVDVLCC 134

  Fly   238 TASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQQF 302
            ||||:.||.||:|||..:..||:||..||::...:.||..|:...::|..|:| ||      :|.
 Frog   135 TASIMSLCAISIDRYIGVSYPLRYPSIMTEKRGVLALLCIWVLSLVISIGPLF-GW------KQP 192

  Fly   303 VIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQL----MMRHGNA---- 359
            ..::...|.......||:.|:..||::|.:|::..|..::..|.|:.|.|    .:...::
 Frog   193 APEDDKICEITKEPGYALFSAFGSFYLPLSIILVMYFRVYIVAKRESKVLTSGMKLEKSDSEEVT 257

  Fly   360 MLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTFILCW 424
            :.:||.|   :.|::..:.|||..|...|          .|:|..||.|||:||||::|.|:|||
 Frog   258 LRIHRKS---TPESIGSTSSSKQKTQFSV----------RLLKFSREKKAAKTLGIVVGCFVLCW 309

  Fly   425 LPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLCLFCNWWK 489
            |||||...:..........|.:..|.||:|||||.:||:||...:.:||:||:|.|
 Frog   310 LPFFLVMPIGSIYPPANSSDTIFKITFWLGYFNSCINPVIYPCSSPEFRKAFQNIL--------- 365

  Fly   490 DRHLPLDIDIRRSSLRYDQRAKSVYSESY-LNSTTPSHRRQSQ 531
                       .:...:.::|.|.||..: |||  |.||...:
 Frog   366 -----------HARCSHRRQAASKYSSGFLLNS--PVHRSSEE 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	61/177 (34%)
		7tm_1	170..465	CDD:278431	105/302 (35%)
adra1a	XP_002933012.2	7tmA_alpha1A_AR	51..361	CDD:320448	112/329 (34%)
		TM helix 1	52..78	CDD:320448	10/25 (40%)
		TM helix 2	85..111	CDD:320448	9/25 (36%)
		TM helix 3	123..153	CDD:320448	15/29 (52%)
		TM helix 4	165..188	CDD:320448	6/23 (26%)
		TM helix 5	205..234	CDD:320448	8/28 (29%)
		TM helix 6	289..319	CDD:320448	19/29 (66%)
		TM helix 7	329..354	CDD:320448	13/24 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910