DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Octbeta2R and taar19k

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_002663679.2	Gene:	taar19k / 100151309	ZFINID:	ZDB-GENE-091116-71	Length:	334	Species:	Danio rerio

Alignment Length:	318	Identity:	94/318 - (29%)
Similarity:	146/318 - (45%)	Gaps:	72/318 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 NLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVY 235
            |||||||:...:||...||..::|||:||:::.:: |.......:...|.|....|.|:.....:
Zfish    49 NLLVIISISHFKKLHTPTNMIILSLAVADLLLGVV-MPVEAIRLIEMCWYFGDIFCGLYLLFISF 112

  Fly   236 FSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGW-YTTPQH 299
            ..:||:.:|..|:||||.|:..||:||..:|            ||..|:|   |.:.| |:|..:
Zfish   113 LISASLSNLILIAVDRYMAVCHPLQYPQKIT------------ISKTLMS---ICLSWVYSTVYN 162

  Fly   300 QQFVIQN------PT------QCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQL 352
            ...||.|      |.      ||||.::..:..:...:|...||.::|..||.||...::|
Zfish   163 STLVISNGHFDTSPRTDVCYGQCSFDMSFSWIAVDMFMSLIFPCMLIITLYLRIFYVVHKQ---- 223

  Fly   353 MMRHGNAMLMHRPSMQPSGE-ALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGII 416
                  .|:::  |:...|: .:.||                       :|.|.|.|||..||||
Zfish   224 ------VMVIN--SLMKGGKCVVRGS-----------------------VKRKSESKAALILGII 257

  Fly   417 MGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFRE 474
            :..::||::|:.:   .|:|.:.    ...:..|.|..|.||.|||||||.|...|::
Zfish   258 VSVYLLCYIPYCI---CSLTVKS----STAIHSLIWAVYSNSGLNPLIYALFYPWFKK 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	57/183 (31%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	89/307 (29%)
taar19k	XP_002663679.2	7tmA_TAARs	32..309	CDD:320183	94/318 (30%)
		TM helix 1	33..59	CDD:320183	7/9 (78%)
		TM helix 2	66..91	CDD:320183	8/25 (32%)
		TM helix 3	103..133	CDD:320183	11/29 (38%)
		TM helix 4	145..168	CDD:320183	8/25 (32%)
		TM helix 5	190..219	CDD:320183	8/28 (29%)
		TM helix 6	245..275	CDD:320183	13/32 (41%)
		TM helix 7	278..303	CDD:320183	12/24 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910