DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and taar20u

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_021328040.1	Gene:	taar20u / 100151047	ZFINID:	ZDB-GENE-060414-17	Length:	357	Species:	Danio rerio

Alignment Length:	334	Identity:	98/334 - (29%)
Similarity:	164/334 - (49%)	Gaps:	56/334 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 IVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQV 215
            |::||.:.:....:..    |||||||:...:||...||..::|||:.|:::.:: |.......:
Zfish    58 IIYVFVSLLSAWTVFL----NLLVIISISHFKKLHTPTNMIILSLAVTDLLIGLI-MPVEAIRLI 117

  Fly   216 TGRWNFSPFLCDLW-NSLDVYFSTASILHLCCISVDRYYAIVKPLKYP--ISMTKRVVGIMLLNT 277
            ...|.|....|:|: ..:|:..|| |:.:|..|:||||.|:..||.||  |::||.::.|.|  .
Zfish   118 ETCWYFGDTFCELYLLFVDLLIST-SLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICL--G 179

  Fly   278 W-ISPALLSFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAI 341
            | .|.|.:..:.|...::.| .|:..|...  :|..:::..:.|....:||..||.::|..||.|
Zfish   180 WACSSAYIIAIAINNRYFDT-SHRTDVCYG--ECLAIISFNWTVTDLFMSFIFPCFVIIMLYLRI 241

  Fly   342 FREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKRE 406
            |...::|.|.:     |:::       ..|:.:: .||                     :|.|.|
Zfish   242 FYVVHQQVKVI-----NSLI-------KGGKCVT-EGS---------------------VKRKSE 272

  Fly   407 HKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRD 471
            .|||.|||||:..::|||:|:::       |....:....::.|.|:.|.||.||||:||.|...
Zfish   273 SKAALTLGIIVTVYLLCWIPYYI-------CSLTVMTSTALNALLWVVYANSGLNPLVYALFYPW 330

  Fly   472 FREAFRNTL 480
            |::..:.||
Zfish   331 FKKTAQLTL 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	56/181 (31%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	89/298 (30%)
taar20u	XP_021328040.1	7tmA_TAARs	57..334	CDD:320183	96/327 (29%)
		TM helix 1	58..84	CDD:320183	10/29 (34%)
		TM helix 2	91..116	CDD:320183	7/25 (28%)
		TM helix 3	128..158	CDD:320183	13/30 (43%)
		TM helix 4	170..193	CDD:320183	7/24 (29%)
		TM helix 5	215..244	CDD:320183	10/28 (36%)
		TM helix 6	270..300	CDD:320183	15/36 (42%)
		TM helix 7	303..328	CDD:320183	11/24 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910