DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta2R and taar20o

DIOPT Version :9

Sequence 1:	NP_001163596.2	Gene:	Octbeta2R / 41549	FlyBaseID:	FBgn0038063	Length:	630	Species:	Drosophila melanogaster
Sequence 2:	XP_017213636.2	Gene:	taar20o / 100002324	ZFINID:	ZDB-GENE-060414-4	Length:	350	Species:	Danio rerio

Alignment Length:	306	Identity:	90/306 - (29%)
Similarity:	146/306 - (47%)	Gaps:	48/306 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 NLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVY 235
            |||||||:...:||...||..::|||:.|::|.:: |.......:...|.|....|.|:......
Zfish    67 NLLVIISISHFKKLHTPTNMIILSLAVTDLLVGLV-MPVEAIRLIETCWYFGDTFCGLYIFFVSL 130

  Fly   236 FSTASILHLCCISVDRYYAIVKPLKYP--ISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQ 298
            ..:||:.:|..|:||||.|:..||.||  |::||.::.|.|  :|..........:....|....
Zfish   131 LLSASLGNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICL--SWAGLTAYIITLVINNSYFDTS 193

  Fly   299 HQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMH 363
            |:..|...  ||.::::..:.:....:||..||.::|..||.||...::|.|.:
Zfish   194 HRTDVCYG--QCLYMISYSWILTELFMSFIFPCILIITLYLRIFYVVHQQVKVI----------- 245

  Fly   364 RPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTFILCWLPFF 428
             .|:...|:.:: .||                     :|.|.|.|||.|||||:..::|||:|:|
Zfish   246 -NSLMKGGKCVT-EGS---------------------VKRKSESKAALTLGIIVSVYLLCWIPYF 287

  Fly   429 LWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFRE 474
            : |:|::...     ..:..:||.: :.||.||||:||.|...|::
Zfish   288 I-YSLTVNAS-----TTINGLLFAV-FANSGLNPLVYALFYPWFKK 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta2R	NP_001163596.2	7tm_4	164..>342	CDD:304433	52/172 (30%)
Octbeta2R	NP_001163596.2	7tm_1	170..465	CDD:278431	86/295 (29%)
taar20o	XP_017213636.2	7tmA_TAARs	50..327	CDD:320183	90/306 (29%)
		TM helix 1	51..77	CDD:320183	7/9 (78%)
		TM helix 2	84..109	CDD:320183	8/25 (32%)
		TM helix 3	121..151	CDD:320183	11/29 (38%)
		TM helix 4	163..186	CDD:320183	5/24 (21%)
		TM helix 5	208..237	CDD:320183	9/28 (32%)
		TM helix 6	263..293	CDD:320183	17/30 (57%)
		TM helix 7	296..321	CDD:320183	10/30 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910