DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5961 and Fbxo9

DIOPT Version :9

Sequence 1:	NP_001189211.1	Gene:	CG5961 / 41541	FlyBaseID:	FBgn0038056	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	XP_038937077.1	Gene:	Fbxo9 / 300849	RGDID:	1310374	Length:	471	Species:	Rattus norvegicus

Alignment Length:	488	Identity:	166/488 - (34%)
Similarity:	238/488 - (48%)	Gaps:	85/488 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DSDGEEPTRKTGTNALDEFRENWQRELQEHTTNTGS----------------RSHSEAGDRLTAA 53
            |...|.|..:.....|..||..|..||   |...||                ::.::.|.:..|.
  Rat    18 DEGHESPAERDLQAQLQMFRAQWMFEL---TPGVGSSNVESRPCRAGRSSILKAAADKGRQELAK 79

  Fly    54 NSNLSEADLLQ--------------------------AKAESLYRTAVQLEQRGKVYDALPFYRK 92
            ...|| |::||                          .:|..|:..||:.||.|.:|:|:.|||:
  Rat    80 EEKLS-AEILQQTKSCFRHSASHQCVCHLSTLRTEAVCEARELFLKAVEEEQNGALYEAIKFYRR 143

  Fly    93 ATQIVPDIEFRF-YEQQKQKLSNDVSKKYLNLANDLAKQLDLGQSDGEEVVDNLYEKFQHDLR-Q 155
            |.|:||||||:. |.:...  .:.|...|:....|.:|..|            |...||..|. |
  Rat   144 AMQLVPDIEFKITYTRSPD--GDGVGSSYIEDNEDASKMAD------------LLSYFQQQLTFQ 194

  Fly   156 KNIYNGKMIASSRDANVLTTGLHFADLPPEIVMRILRWVVSAQLDMRSLEQCAAVCKGFYVYARD 220
            :::.  |:.....:    |:..|.:.||.|::|.|.|||||:.||:|||||.:.||:|||:.|||
  Rat   195 ESVL--KLCQPELE----TSQTHISVLPMEVLMYIFRWVVSSDLDLRSLEQLSLVCRGFYICARD 253

  Fly   221 EELWRLACVKVWGHNVGTLEAQDSDVSNVFHSWRDMFIRRDRVLFNGCYISKTTYLRMGENSFQD 285
            .|:|||||:||||.:...|..        |.|||:||:.|.||.|:|.|||||||:|.||.|. |
  Rat   254 PEIWRLACLKVWGRSCMKLVP--------FSSWREMFLERPRVRFDGVYISKTTYIRQGEQSL-D 309

  Fly   286 QFYRPVQLVEYYRYIRFLPDGKVLMMTTADEPAQGVSKLKHVNNVRAEMLRGRYRLF-----GST 345
            .|||....|||||||||.|||.|:|:||.:||...|.:|:..|.....:|.|.|||.     .:.
  Rat   310 GFYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPPSIVPRLRTRNTRTDAILLGHYRLSQDADNQTK 374

  Fly   346 VTLVLQKSQQRGPANVRQRRGSIMPVDEDSSQFLIELRIAGTTKRRCAQLVWSHYT--LVQKRNK 408
            |..|:.|.::..|.:.:.|....:||.|....|.:.|::..:..:|..:|:|.|::  :..:...
  Rat   375 VFAVITKKKEEKPLDHKYRYFRRVPVQEADHNFHVGLQLCSSGHQRFNKLIWIHHSCHITYRSTG 439

  Fly   409 VDISSEFDLTEAKYPALRFSTVKSYHLDADAPL 441
            ....|.||: :..|..|.|:.|:||...::.||
  Rat   440 ETAVSAFDI-DKMYTPLFFARVRSYTAFSERPL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5961	NP_001189211.1	MIT	74..131	CDD:294211	23/57 (40%)
CG5961	NP_001189211.1	F-box-like	179..225	CDD:289689	26/45 (58%)
Fbxo9	XP_038937077.1	F-box-like	212..258	CDD:403981	26/45 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346238
Domainoid	1	1.000	131	1.000	Domainoid score	I5043
eggNOG	1	0.900	-	-		E1_KOG2997
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8217
Inparanoid	1	1.050	244	1.000	Inparanoid score	I3214
OMA	1	1.010	-	-		QHG46930
OrthoDB	1	1.010	-	-		D1407789at2759
OrthoFinder	1	1.000	-	-		FOG0005835
OrthoInspector	1	1.000	-	-		oto98029
orthoMCL	1	0.900	-	-		OOG6_104095
Panther	1	1.100	-	-	LDO	PTHR12874
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4819
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770