DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5961 and pof7

DIOPT Version :9

Sequence 1:	NP_001189211.1	Gene:	CG5961 / 41541	FlyBaseID:	FBgn0038056	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_588546.2	Gene:	pof7 / 2539142	PomBaseID:	SPCC1827.08c	Length:	361	Species:	Schizosaccharomyces pombe

Alignment Length:	429	Identity:	98/429 - (22%)
Similarity:	179/429 - (41%)	Gaps:	106/429 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 SEAGDRLTAANSNLSEADLLQAKAESLYRTAVQLEQRGKVYDALPFYRKATQIVPDIE--FRFYE 106
            |...|:|:.....::: |:|..||...|:.|::.|:.|.:.::|..||.|.::..|:|  :|..|
pombe     2 STVEDQLSLELETVNK-DILLKKALLHYKDAIKSEREGNLGESLNKYRLAHKVHEDVESIYRRLE 65

  Fly   107 --------QQKQKLSNDVSKKYLNLANDLAKQLDLGQSDGEEVVDNLYEKFQHDLRQKNIYNGKM 163
                    ::::.|::|.|:..|.:::..:..|...:|..|.||.|:.:
pombe    66 RLQLCKRNEEEEMLNSDASEAMLTVSSVPSPTLTENESVNESVVPNILK---------------- 114

  Fly   164 IASSRDANVLTTGLHFADLPPEIVMRILRWVVSAQLDMRSLEQCAAVCKGFYVYARDEELWRLAC 228
                              ||.|:::.||...:....|:|.|...|..||.|....|.:.|:|..|
pombe   115 ------------------LPDEVLLVILENCIRDLHDLRYLSSIALTCKHFAKALRADSLYRSFC 161

  Fly   229 V-----KVWGHNVGTLEAQDSDVSNVFHSWRDMFIRRDRVLFNGCYISKTTYLRMGENSFQDQFY 288
            .     |.|..::.::|  :..|.....||:.:|:::.|..|:|||||...|.|.|.:  ...:.
pombe   162 YCSCEQKEWQQSIKSIE--EELVEKYQQSWKTLFLKKPRSRFDGCYISVCRYFRPGTS--DTSWN 222

  Fly   289 RPVQLVEYYRYIRFLPDGKVLMMTTADEPAQGVSKLKHVN----------------NVRAEMLRG 337
            :|:.|:.||||:|..|:...::..:::||...|......|                ||   .|.|
pombe   223 QPIHLITYYRYLRLYPNSTCIVYQSSNEPNDVVRNFSVQNTSLFSPMSSSPMFSNGNV---ALTG 284

  Fly   338 RYRLFGSTVTLVLQKSQQRGPANVRQRRGSIMPVDEDSSQFLIELRIAGTTKRRCAQLVW-SHYT 401
            .:.:..|...|::..:.|                   :..::.:|::.|      .:|.| |.|:
pombe   285 SWSMTPSGEMLIVYPASQ-------------------TYTYVQKLQVRG------IRLKWISFYS 324

  Fly   402 LVQKRNKVDISSEFDLTEAK-YPALRFSTVKSYHLDADA 439
            :   .|....::|..||..: |.   ||.|.||..|:::
pombe   325 I---HNYTSFTNEMPLTHNRDYV---FSRVYSYTADSES 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5961	NP_001189211.1	MIT	74..131	CDD:294211	15/66 (23%)
CG5961	NP_001189211.1	F-box-like	179..225	CDD:289689	14/45 (31%)
pof7	NP_588546.2	F-box-like	112..161	CDD:289689	15/82 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2997
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I1732
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005835
OrthoInspector	1	1.000	-	-		oto101753
orthoMCL	1	0.900	-	-		OOG6_104095
Panther	1	1.100	-	-	LDO	PTHR12874
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R949
SonicParanoid	1	1.000	-	-		X4819
TreeFam	0	0.000	Not matched by this tool.
	10	9.890