DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5961 and LOC101732478

DIOPT Version :9

Sequence 1:	NP_001189211.1	Gene:	CG5961 / 41541	FlyBaseID:	FBgn0038056	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	XP_004914495.1	Gene:	LOC101732478 / 101732478	-ID:	-	Length:	417	Species:	Xenopus tropicalis

Alignment Length:	398	Identity:	72/398 - (18%)
Similarity:	146/398 - (36%)	Gaps:	118/398 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LYRTAVQLEQRGKVYDALPFYRKATQIVPDIEFRFYEQQKQKLSNDVSKKYLNLANDLAKQLDLG 134
            |..||:||::   ::|::.. .|:.:::         ::..:|......::..|.:.:...|:..
Frog     9 LVETALQLQE---LHDSISL-SKSERLI---------RRTGRLKQWQLDRFPPLCSSVTHSLENK 60

  Fly   135 QSDGEEVVDNLYEKFQHDLRQKN-IYNGKMIASSRDA---NVLTTGLHFADLPPEIVMRILRWVV 195
            ::...|.|.      :.|:.|.| :.|..:..:.:|.   ::|.:.....||  .:|..:|:...
Frog    61 KTSLHEAVR------RGDMDQVNTLLNFGIAVNCQDYRGWSLLHSAAFCGDL--ALVKYLLQKGA 117

  Fly   196 SAQL-DMRS------------------LEQCAAVCKGFYVYARDEEL------WRLACVKVWGHN 235
            |..| |:||                  |.||.|: .....|..:..|      ..|.|||:...|
Frog   118 SVNLRDVRSYTPLHRAAWTGHAELTDYLLQCGAL-PDIVNYCGETPLHLAAANGHLLCVKILIQN 181

  Fly   236 VGTLEAQDSDVSNVFHSWRDMFIRRDRVLFNGCYISKTTYLRMGENSFQDQFYRPVQLVEYYRYI 300
            ..:::.:|:      :.|..:         ..|             |..||    :.::||.
Frog   182 KASIDIKDN------NKWTPL---------QWC-------------SINDQ----IDVLEYL--- 211

  Fly   301 RFLPDGKVLMMTTADEPAQGVSKLKHVNNVRAEMLRGRYRLFGSTVTL---------VLQKSQQR 356
                   |.:..:.:|.:.....|.|::.:...:....| |..:.|.:         .|..:.:.
Frog   212 -------VSLGASLEEKSTTGMTLLHLSALAGNLQVINY-LLNTNVDINVKDINGLTALHLAAEN 268

  Fly   357 GPANVRQ---RRGSIMPVDEDSSQFLIELRIAGTTKRRCAQLVWSHYTLVQKR----NKVDISSE 414
            |.:.:.:   ::|:|:.: .|.:......|.||   |...::|    ||:.|:    |.:||.:.
Frog   269 GHSKIIKCLLKKGAIVNI-TDINHLTPLHRAAG---RGYTEIV----TLLLKQKAAVNNMDIQNL 325

  Fly   415 FDLTEAKY 422
            ..|..|.|
Frog   326 TPLHHAAY 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5961	NP_001189211.1	MIT	74..131	CDD:294211	7/56 (13%)
CG5961	NP_001189211.1	F-box-like	179..225	CDD:289689	15/70 (21%)
LOC101732478	XP_004914495.1	Ank_4	62..113	CDD:372654	11/58 (19%)
		ANK repeat	62..90	CDD:293786	6/33 (18%)
		ANK repeat	92..123	CDD:293786	7/32 (22%)
		PHA03095	105..>375	CDD:222980	54/283 (19%)
		ANK repeat	125..156	CDD:293786	6/31 (19%)
		ANK repeat	158..189	CDD:293786	6/30 (20%)
		ANK repeat	191..219	CDD:293786	8/63 (13%)
		ANK repeat	227..255	CDD:293786	5/28 (18%)
		ANK repeat	257..288	CDD:293786	4/31 (13%)
		ANK repeat	290..321	CDD:293786	9/37 (24%)
		ANK repeat	323..354	CDD:293786	3/11 (27%)
		ANK repeat	356..387	CDD:293786
		Ank_4	359..407	CDD:372654
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165171267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12874
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030